tag:blogger.com,1999:blog-8581701599170312782024-03-13T12:04:00.128-04:00THE CSHL ARCHIVES BLOGJohn Zarrillohttp://www.blogger.com/profile/10955424654611881866noreply@blogger.comBlogger62125tag:blogger.com,1999:blog-858170159917031278.post-35794694092537592892013-05-22T14:26:00.000-04:002013-05-23T13:55:22.041-04:00Evelyn Witkin Collection<!--[if gte mso 9]><xml>
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following is another post in our series highlighting the collections
that are being processed through the NHPRC Basic Processing Grant.</i></span><br />
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<tr><td style="text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhToo2ZXAnFf5AqyeCop3Qr5nXaMg3yGxi6NQBf1P7lNXXL0bXyf0r7R47Dw1QMNScqXbG_6Hr33A5HBkcltmA-oK3SGToWdHvUOsLkD6wB61fGzpARrC8CIy-cY8SNw5wEy4s3SF-TnS6z/s1600/witkin.jpg" imageanchor="1" style="margin-left: auto; margin-right: auto;"><img border="0" height="318" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhToo2ZXAnFf5AqyeCop3Qr5nXaMg3yGxi6NQBf1P7lNXXL0bXyf0r7R47Dw1QMNScqXbG_6Hr33A5HBkcltmA-oK3SGToWdHvUOsLkD6wB61fGzpARrC8CIy-cY8SNw5wEy4s3SF-TnS6z/s320/witkin.jpg" width="320" /></a></td></tr>
<tr><td class="tr-caption" style="text-align: center;">Witkin and A.H. Sparrow at the 1947 CSH Symposium</td></tr>
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<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">Evelyn M. Witkin is an American geneticist whose research
has been widely influential in the areas of DNA mutagenesis and DNA repair.</span></div>
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<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">The Evelyn Witkin Collection at Cold Spring Harbor
Laboratory consists of three series including Dr. Witkin’s professional
correspondence with Nobelist Barbara McClintock, Joshua Lederberg, and Ruth
Sager among others. There is a complete collection of her personal reprints as
well as historical documents related to her work on the “SOS Response”.</span></div>
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<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><span style="mso-spacerun: yes;"> </span>Witkin’s connection
to Cold Spring Harbor Laboratory is through her work at the Carnegie
Institution of Washington’s Department of Genetics where she was a staff scientist
from 1945 until 1955. During her time at the Department of Genetics, she
isolated a UV radiation-resistant mutant of <i style="mso-bidi-font-style: normal;">E.
coli</i>, the first time this work had been done. </span></div>
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<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">Dr. Witkin is a frequent visitor to Cold Spring Harbor
Laboratory.<span style="mso-spacerun: yes;"> </span>Dr. Witkin participated in
the CSHL Oral History Project in and her interview can be viewed on the Oral
History Office website at <a href="http://library.cshl.edu/oralhistory/speaker/evelyn-witkin/">http://library.cshl.edu/oralhistory/speaker/evelyn-witkin/</a>. </span><br />
<br />
<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">- C.C., Archivist </span></div>
John Zarrillohttp://www.blogger.com/profile/10955424654611881866noreply@blogger.com0tag:blogger.com,1999:blog-858170159917031278.post-32726840037802287972013-05-22T14:13:00.001-04:002013-05-24T10:02:33.024-04:00The Office of Technology Transfer Collection<!--[if gte mso 9]><xml>
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</xml><![endif]--><span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif; font-size: small;"><i>The
following is another post in our series highlighting the collections
that are being processed through the NHPRC Basic Processing Grant.</i></span><br />
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<br />
<div class="separator" style="clear: both; text-align: center;">
<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><span style="font-size: small;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEj0_UTTxCaqwW7I3Cp0gvVTwOckVqxmAtuXDzMONSgaDzOvbRgMidvjjqBPELQGO-Qw-yxDmvR3Odgw0jW-vaJXGtYfzvadOJC2_XGYUZJzsvXHoUBlNaeESrqUFYr_9glkLUAeaYQ1lrUu/s1600/Biotech.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="320" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEj0_UTTxCaqwW7I3Cp0gvVTwOckVqxmAtuXDzMONSgaDzOvbRgMidvjjqBPELQGO-Qw-yxDmvR3Odgw0jW-vaJXGtYfzvadOJC2_XGYUZJzsvXHoUBlNaeESrqUFYr_9glkLUAeaYQ1lrUu/s320/Biotech.jpg" width="239" /></a></span></span></div>
<div class="MsoNormal" style="margin-bottom: 0.0001pt;">
<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><span style="font-size: small;"><span style="line-height: 115%;">The
Office of Technology Transfer Collection documents CSHL’s first inroads into
the world of Biotechnology. Research
that was initially carried out in academic laboratories led to the development
of recombinant DNA techniques. This in
turn stimulated entrepreneurial scientists to create biotechnology companies.
Recombinant DNA is the technology that allows us to insert genes from one
organism into another to make it produce a protein product, copy the gene
multiple times, or give it a new trait. The discovery of recombinant DNA was
considered the "birth" of modern biotechnology. </span></span></span></div>
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<br /></div>
<div class="MsoNormal" style="margin-bottom: 0.0001pt;">
<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><span style="font-size: small;"><span style="line-height: 115%;">CSHL
has always been on the forefront of scientific research and discoveries. Thus, it was a natural progression that the
Lab should move into biotechnology. Here we will show a brief overview of three
early forays.</span></span></span></div>
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<br /></div>
<div class="MsoListParagraph" style="margin: 0in 0in 0.0001pt 0.25in; text-indent: -0.25in;">
<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><span style="font-size: small;"><span style="line-height: 115%;">1.<span style="-moz-font-feature-settings: normal; -moz-font-language-override: normal; font-size-adjust: none; font-stretch: normal; font-style: normal; font-variant: normal; font-weight: normal; line-height: normal;">
</span></span><span style="line-height: 115%;"> <b>Cellbiology Corporation</b>, a
biotechnology company established in 1980, was a wholly owned for-profit
subsidiary of Cold Spring Harbor Laboratory. It was originally conceived as the
commercial arm of the Lab and as an entity that would initiate CSHL into the
biotech world and harness the developments in gene splicing and recombinant DNA
techniques. Cellbiology was used for a
few projects in the early-to-mid 1980s, but it never developed into a long-term
concern. The most significant work
occured in 1982: Cellbiology Corporation signed a contract with Baxter
Travenol, "covering the development of Tissue Plasminogen Activator (tPA)
as a potentially useful pharmaceutical product to dissolve blood
clots." Together, the two
companies contracted to work with the Genetics Institute in Boston on the Activator. In July 1984, Baxter Travenol sold its
interests in tPA technology to Burroughs Wellcome. Cellbiology Corporation was
kept mostly dormant from the mid-1980s on, and it was dissolved in 1995. </span></span></span></div>
<div style="line-height: 115%; margin: 0in 0in 0.0001pt;">
<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><span style="font-size: small;"><b><u><span style="text-decoration: none;"><br /></span></u></b></span></span></div>
<table align="center" cellpadding="0" cellspacing="0" class="tr-caption-container" style="margin-left: auto; margin-right: auto; text-align: center;"><tbody>
<tr><td style="text-align: center;"><span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><span style="font-size: small;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjlvpuoltglxYDVRA53kVPDgvDFJRkMkoGOxlxVTfOjKr1PnIlieNY3VhZKcB775KQSCDZrrByuXiTRsbt9OSw6wmI4eJUsuAtQfS7D1_NIw7lJKe-rWVOnXFZmM1fbMOil4G7_BfNC6sOd/s1600/Ed+Harlow+and+URP++Abhjeet+Lele+1986.jpg" imageanchor="1" style="margin-left: auto; margin-right: auto;"><img border="0" height="257" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjlvpuoltglxYDVRA53kVPDgvDFJRkMkoGOxlxVTfOjKr1PnIlieNY3VhZKcB775KQSCDZrrByuXiTRsbt9OSw6wmI4eJUsuAtQfS7D1_NIw7lJKe-rWVOnXFZmM1fbMOil4G7_BfNC6sOd/s320/Ed+Harlow+and+URP++Abhjeet+Lele+1986.jpg" width="320" /></a></span></span></td></tr>
<tr><td class="tr-caption" style="text-align: center;"><span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><span style="font-size: small;">Dr.
Harlow in 1986 with URP student Abhjeet Lele</span></span></td></tr>
</tbody></table>
<div style="line-height: 115%; margin: 0in 0in 0.0001pt;">
<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><span style="font-size: small;"><b><u><span style="text-decoration: none;"></span></u></b></span></span></div>
<div style="line-height: 115%; margin: 0in 0in 0.0001pt 0.25in;">
<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><span style="font-size: small;">2.<span style="-moz-font-feature-settings: normal; -moz-font-language-override: normal; font-size-adjust: none; font-stretch: normal; font-style: normal; font-variant: normal; font-weight: normal; line-height: normal;">
</span> <b>Ed Harlow:</b> In 1988, while working at CSHL, Ed
Harlow and his colleagues established "a crucial functional link
between the two general classes of cancer-causing genes (oncogenes and
tumor-suppressor genes)". Oncogenes (tumor inducing genes) induce changes in cell
phenotype. Adenovirus oncogene E1A can
immortalize primary cells and can also cooperate with the adenovirus E1B gene
or other oncogene to transform cells in culture. The transformed cells will induce tumors in
animals. E1A encoded proteins are potent
regulators of gene expression able to modulate transcription of both viral and
cellular genes. E1A proteins activate
transcription of the other adenovirus early genes and certain cellular
genes. They also repress transcription
of genes linked to certain viral or cellular enhancers.</span></span></div>
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<br /></div>
<div class="MsoNormal" style="margin: 0in 0in 0.0001pt 0.25in;">
<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><span style="font-size: small;"><span style="line-height: 115%;">In addition to his work
on oncogens, while at CSHL, Dr. Harlow and Nick Dyson worked under a
relationship between CSHL and Amersham on monoclonal antibodies. Dr. Harlow left CSHL in February of 1991 to
become scientific director at Massachusetts General Hospital in Boston. </span></span></span></div>
<div style="line-height: 115%; margin: 0in 0in 0.0001pt;">
<br /></div>
<div style="line-height: 115%; margin: 0in 0in 0.0001pt 0.25in; text-indent: -0.25in;">
<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><span style="font-size: small;">3.<span style="-moz-font-feature-settings: normal; -moz-font-language-override: normal; font-size-adjust: none; font-stretch: normal; font-style: normal; font-variant: normal; font-weight: normal; line-height: normal;">
</span> <b>ICOS Corp</b>. was founded in early 1990 as
a Seattle-based drug discovery company specializing in inflammatory
diseases. ICOS was founded by three men: George Rathmann, founder of Amgen;
Robert Nowinski, founder of Genetic Systems Corporation; and Christopher
Henney, founder of Immunex Corporation.</span></span></div>
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<br /></div>
<div class="MsoNormal" style="margin: 0in 0in 0.0001pt 0.25in;">
<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><span style="font-size: small;"><span style="line-height: 115%;">The formal relationship
between CSHL and ICOS began in April 1990 with a licensing agreement under
which ICOS was obligated to pay CSHL royalties for all PDE [phosphodiesterase]
products developed by ICOS that used Michael Wigler's patented techniques. ICOS eventually developed the popular drug
Cialis from Dr. Wigler's technology. This portion of the Collection is restricted
due to confidentiality obligations between ICOS and CSHL.<span style="color: black;"></span></span></span></span></div>
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<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><span style="font-size: small;"><span style="line-height: 115%;">Here is a photo of </span><span style="color: black; line-height: 115%;">the early scientists and administrators involved
with ICOS, circa 1990. </span></span></span></div>
<div class="separator" style="clear: both; text-align: center;">
<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><span style="font-size: small;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhXF3HQEHaXM4ypN-swR-YX6jc7ZUBqE8eqg2kQ8P5zeRBgDpMjT_lr9EbP_BCReR5O7kOrsagqw-ECFhni0ODzeOK45F7KHEuRqTlLyhnmoxZqgEueTdock_7llKsV3A21zRzURrEJmnmF/s1600/ICOS+Group+Photo.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="249" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhXF3HQEHaXM4ypN-swR-YX6jc7ZUBqE8eqg2kQ8P5zeRBgDpMjT_lr9EbP_BCReR5O7kOrsagqw-ECFhni0ODzeOK45F7KHEuRqTlLyhnmoxZqgEueTdock_7llKsV3A21zRzURrEJmnmF/s320/ICOS+Group+Photo.jpg" width="320" /></a></span></span></div>
<div class="MsoNormal">
<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">- Amy Driscoll, Project Archivist</span></div>
John Zarrillohttp://www.blogger.com/profile/10955424654611881866noreply@blogger.com0tag:blogger.com,1999:blog-858170159917031278.post-24318628694971667482013-04-25T13:26:00.000-04:002013-04-25T13:40:18.506-04:00DNA DAY 2013Today is the 60th anniversary of the publication of Watson and Crick's famous paper on the structure of DNA. The CSHL Archives is home to the James D. Watson Collection, which includes many documents related to the discovery. Below is just a selection of items found in the collection, all of which are accessible via our <a href="http://libgallery.cshl.edu/">online repository</a>.<br />
<br />
<table align="center" cellpadding="0" cellspacing="0" class="tr-caption-container" style="margin-left: auto; margin-right: auto; text-align: center;"><tbody>
<tr><td style="text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhn37reF3j79sGzURClcmUrwinEhdF-wkUwL891u8pdJG8RN2Z8Pvzx3dU3hBvctfS2iFcyg8hFuKXnYWpd9fygqyUB7BFceVFUSVYX2xnoGx0_YppJFFFuFDbVEQu1_YNHCNF_3Z3kloZp/s1600/DNA+model.jpg" imageanchor="1" style="margin-left: auto; margin-right: auto;"><img border="0" height="320" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhn37reF3j79sGzURClcmUrwinEhdF-wkUwL891u8pdJG8RN2Z8Pvzx3dU3hBvctfS2iFcyg8hFuKXnYWpd9fygqyUB7BFceVFUSVYX2xnoGx0_YppJFFFuFDbVEQu1_YNHCNF_3Z3kloZp/s320/DNA+model.jpg" width="222" /></a></td></tr>
<tr><td class="tr-caption" style="text-align: center;">Original model of DNA, used in Watson's <i>The Double Helix</i>.<br />
Courtesy of the <a href="http://libgallery.cshl.edu/items/show/51235">James D. Watson Collection</a></td></tr>
</tbody></table>
<div class="separator" style="clear: both; text-align: center;">
<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEgJFgVk9THCeF5PneFpnvXNXy2fAmHmlS9Yy_VVP3DB-JxjGjVZMWQELVHgyB1qKQMCT-P9kzF6IMSw_UAFsy1hY_9oITAC8yGJxxIhiQhu91OMvtuzQ9zF0_Lh_zS25TbB6yonqgpqve-V/s1600/NY+Times+clipping+1.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="320" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEgJFgVk9THCeF5PneFpnvXNXy2fAmHmlS9Yy_VVP3DB-JxjGjVZMWQELVHgyB1qKQMCT-P9kzF6IMSw_UAFsy1hY_9oITAC8yGJxxIhiQhu91OMvtuzQ9zF0_Lh_zS25TbB6yonqgpqve-V/s320/NY+Times+clipping+1.jpg" width="67" /></a><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEi4kaBzNTbpi94g_QN9O4pULeQc0ZtYr4saVL4TbInDsRvTjOGmrG3-7nYIDmkvMBctJM2YcTuzy2M8TeWfA4ZeFeywzyqHOI48bElvrQnWCc0ZPUIeCGAJJgc0dXp79JJjqaQd6TWAdLnB/s1600/NY+Times+clipping+2.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="320" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEi4kaBzNTbpi94g_QN9O4pULeQc0ZtYr4saVL4TbInDsRvTjOGmrG3-7nYIDmkvMBctJM2YcTuzy2M8TeWfA4ZeFeywzyqHOI48bElvrQnWCc0ZPUIeCGAJJgc0dXp79JJjqaQd6TWAdLnB/s320/NY+Times+clipping+2.jpg" width="89" /></a></div>
<div style="text-align: center;">
<span style="font-size: x-small;">New York Times clipping regarding DNA structure discovery, 1953.<br />Courtesy of the <a href="http://libgallery.cshl.edu/items/show/52390">James D. Watson Collection</a></span></div>
<div style="text-align: center;">
<span style="font-size: x-small;"><br /></span></div>
<table align="center" cellpadding="0" cellspacing="0" class="tr-caption-container" style="margin-left: auto; margin-right: auto; text-align: center;"><tbody>
<tr><td style="text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEgC8y2LS9jisxw02551ZgNViJWk4koxoamgC7grEEiXYWpVfDLsaux3g_KvbbqaEoFeO1IDsuaI1seqsnp6QHBtx-WRpv91XZizrpvsq9z_o4u4ayLzrCL1u8pKU-T77vGshqX60xvDyCvH/s1600/Crick+Watson+Freddie.jpg" imageanchor="1" style="margin-left: auto; margin-right: auto;"><img border="0" height="203" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEgC8y2LS9jisxw02551ZgNViJWk4koxoamgC7grEEiXYWpVfDLsaux3g_KvbbqaEoFeO1IDsuaI1seqsnp6QHBtx-WRpv91XZizrpvsq9z_o4u4ayLzrCL1u8pKU-T77vGshqX60xvDyCvH/s320/Crick+Watson+Freddie.jpg" width="320" /></a></td></tr>
<tr><td class="tr-caption" style="text-align: center;">Crick, Herbert "Freddie" Gutfreund, and Watson in Cambridge, 1953.<br />
Courtesy of the <a href="http://libgallery.cshl.edu/items/show/51761">James D. Watson Collection</a></td></tr>
</tbody></table>
<table align="center" cellpadding="0" cellspacing="0" class="tr-caption-container" style="margin-left: auto; margin-right: auto; text-align: center;"><tbody>
<tr><td style="text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEigrfSFTNhsLE2TKBMIM6yArx6aGguqaMI_tQjiEdU6lvUrA-cE81fGm7sSIMQqYMwWwvb9g2q26iso35OU91XLBVnmUzMD5pkEKivv-wfch7tqGG8789hLi5Z6lL4Mj4QB90djEHFRO4Ad/s1600/crick+bio.jpg" imageanchor="1" style="margin-left: auto; margin-right: auto;"><img border="0" height="320" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEigrfSFTNhsLE2TKBMIM6yArx6aGguqaMI_tQjiEdU6lvUrA-cE81fGm7sSIMQqYMwWwvb9g2q26iso35OU91XLBVnmUzMD5pkEKivv-wfch7tqGG8789hLi5Z6lL4Mj4QB90djEHFRO4Ad/s320/crick+bio.jpg" width="249" /></a></td></tr>
<tr><td class="tr-caption" style="text-align: center;">Draft biography of Francis Crick by Watson, 1960s.<br />
For complete biography please see our online repository.<br />
Courtesy of the <a href="http://libgallery.cshl.edu/items/show/52969">James D. Watson Collection</a></td></tr>
</tbody></table>
<div style="text-align: center;">
<span style="font-size: x-small;"></span></div>
<table align="center" cellpadding="0" cellspacing="0" class="tr-caption-container" style="margin-left: auto; margin-right: auto; text-align: center;"><tbody>
<tr><td style="text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhVH_5qhH98qh2VAdVNszf3Su5iSc9pNFDl3NCQmEpPMEOGuQmxV1SKC_NKOHAtQPNuCJQ2QS90QIRt7_uMeRyYJ5wd_-PT6SH2GwcRH0K9KtkJLLJNbVpwdiPTTatZjx23jGFlX6OdQhjX/s1600/Franklin+letter+2.jpg" imageanchor="1" style="margin-left: auto; margin-right: auto;"><img border="0" height="320" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhVH_5qhH98qh2VAdVNszf3Su5iSc9pNFDl3NCQmEpPMEOGuQmxV1SKC_NKOHAtQPNuCJQ2QS90QIRt7_uMeRyYJ5wd_-PT6SH2GwcRH0K9KtkJLLJNbVpwdiPTTatZjx23jGFlX6OdQhjX/s320/Franklin+letter+2.jpg" width="277" /></a></td></tr>
<tr><td class="tr-caption" style="text-align: center;">Letter from Rosalind Franklin to Watson regarding Tobacco Mosaic Virus and RNA, 1955.<br />
<a href="http://libgallery.cshl.edu/items/show/37170">Courtesy of the James D. Watson Collection</a></td><td class="tr-caption" style="text-align: center;"></td><td class="tr-caption" style="text-align: center;"></td><td class="tr-caption" style="text-align: center;"></td><td class="tr-caption" style="text-align: center;"></td><td class="tr-caption" style="text-align: center;"></td><td class="tr-caption" style="text-align: center;"></td><td class="tr-caption" style="text-align: center;"><br /></td></tr>
</tbody></table>
<table align="center" cellpadding="0" cellspacing="0" class="tr-caption-container" style="margin-left: auto; margin-right: auto; text-align: center;"><tbody>
<tr><td style="text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjWzMXzFbcbQqiBKYqM2UedAZmYdhX79ne791u8qEYRm8mrPgSqh0HHWT3CGyQdt0W3d8tNY415I_kB9w7c5UuXeCS-_d1DZYEJSqjA8rD4cYHI4dxMkiqrsJ_wg-fhrms8douMjrtLc6P0/s1600/Dark+Lady.jpg" style="margin-left: auto; margin-right: auto;"><img border="0" height="320" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjWzMXzFbcbQqiBKYqM2UedAZmYdhX79ne791u8qEYRm8mrPgSqh0HHWT3CGyQdt0W3d8tNY415I_kB9w7c5UuXeCS-_d1DZYEJSqjA8rD4cYHI4dxMkiqrsJ_wg-fhrms8douMjrtLc6P0/s320/Dark+Lady.jpg" width="231" /></a></td></tr>
<tr><td class="tr-caption" style="text-align: center;">"Rosalind Franklin: The Dark Lady of DNA" promotional photograph.<br />
Courtesy of the <a href="http://libgallery.cshl.edu/items/show/51821">James D. Watson Collection</a></td></tr>
</tbody></table>
<table align="center" cellpadding="0" cellspacing="0" class="tr-caption-container" style="margin-left: auto; margin-right: auto; text-align: center;"><tbody>
<tr><td style="text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEixAwwcI0XMM5gp2zcwkXriXrsTLbf3H1Ye0_Msk8RevKtghneJ9062DjpMLGW044Cq7Cgbb0TlD-dfThrwDiGqVBDcaWrPNdGeH87LTeeYD0A3H6oBHB4Hf3nJ4t54u0aZxjId1yPBC9tP/s1600/Franklin+letter.jpg" imageanchor="1" style="margin-left: auto; margin-right: auto;"><img border="0" height="320" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEixAwwcI0XMM5gp2zcwkXriXrsTLbf3H1Ye0_Msk8RevKtghneJ9062DjpMLGW044Cq7Cgbb0TlD-dfThrwDiGqVBDcaWrPNdGeH87LTeeYD0A3H6oBHB4Hf3nJ4t54u0aZxjId1yPBC9tP/s320/Franklin+letter.jpg" width="244" /></a></td></tr>
<tr><td class="tr-caption" style="text-align: center;">Letter from Rosalind Franklin biographer Anne Sayre to Watson, 1970.<br />
Please see our online repository for the rest of the letter.<br />
Courtesy of the <a href="http://libgallery.cshl.edu/items/show/37190">James D. Watson Collection</a></td></tr>
</tbody></table>
<table align="center" cellpadding="0" cellspacing="0" class="tr-caption-container" style="clear: right; margin-bottom: 1em; margin-left: auto; margin-right: auto; text-align: center;"><tbody>
<tr><td style="text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhc_P9RV26vo0wlqCXGc-a2_L1V50CN0hZc1DteF4F0aqYl6n8kMvKONywIgYtfY5CDrhNBJjxBGRi0X3p3teHsI_EF8wT1Ic2QtEHC1S-7otuZjQbMgJx_vOZk3tVxu9Q9hdB3Iqfs9Ryo/s1600/DNA+reading+list.jpg" imageanchor="1" style="margin-left: auto; margin-right: auto;"><img border="0" height="320" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhc_P9RV26vo0wlqCXGc-a2_L1V50CN0hZc1DteF4F0aqYl6n8kMvKONywIgYtfY5CDrhNBJjxBGRi0X3p3teHsI_EF8wT1Ic2QtEHC1S-7otuZjQbMgJx_vOZk3tVxu9Q9hdB3Iqfs9Ryo/s320/DNA+reading+list.jpg" width="248" /></a></td></tr>
<tr><td class="tr-caption" style="text-align: center;">DNA Reading List, c. 1962. Handwritten notation possibly by Francis Crick.<br />
Courtesy of the <a href="http://libgallery.cshl.edu/items/show/37077">James D. Watson Collection</a></td></tr>
</tbody></table>
John Zarrillohttp://www.blogger.com/profile/10955424654611881866noreply@blogger.com0tag:blogger.com,1999:blog-858170159917031278.post-48463560465920146782013-04-25T10:30:00.000-04:002013-04-25T10:32:46.686-04:00Francois Jacob, 1920-2013<table align="center" cellpadding="0" cellspacing="0" class="tr-caption-container" style="margin-left: auto; margin-right: auto; text-align: center;"><tbody>
<tr><td style="text-align: center;"><span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhRuRVWa61yU9_rthWOk0RJTHLSrK75haj9Jjudse1F-7rpwpL4QYry2wS9_t-GcBWlyQdZ-5yRKf2C9Df18vzMsI99BrBbVGHE8HOQTYUe0cIEYLsZy9q4eUG2vjrxVQG7t8p11CcVOBw3/s1600/Jacob+clipping.jpg" imageanchor="1" style="margin-left: auto; margin-right: auto;"><img border="0" height="284" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhRuRVWa61yU9_rthWOk0RJTHLSrK75haj9Jjudse1F-7rpwpL4QYry2wS9_t-GcBWlyQdZ-5yRKf2C9Df18vzMsI99BrBbVGHE8HOQTYUe0cIEYLsZy9q4eUG2vjrxVQG7t8p11CcVOBw3/s320/Jacob+clipping.jpg" width="320" /></a></span></td></tr>
<tr><td class="tr-caption" style="text-align: center;"><span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">Andre Lwoff, Jacques Monod, and Francois Jacob win the Nobel Prize in 1965. <br />Courtesy of the James D. Watson Collection.</span></td><td class="tr-caption" style="text-align: center;"><span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><br /></span></td></tr>
</tbody></table>
<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">Last Friday famed molecular biologist Francois Jacob passed away. Jacob, along with Andrew Lwoff and Jacques Monod, was awarded the 1965 Nobel Prize in Medicine or Physiology for identifying messenger RNA and their work on gene regulation. This research was conducted during the golden age of molecular biology--the period from the late 1940s until the early 1960s when our understanding of genetics grew leaps and bounds. Jacob described the tight-knit community of scientists at the time in an oral history interview for <a href="http://www.webofstories.com/play/14626">Web of Stories</a>:</span><br />
<br />
<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">"</span><span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">There were 15 or 20 guys, always the same ones [at scientific meetings]. Roughly there were Delbrück's guys- there was the Delbrück-Luria group,
Jim [Watson] who came from it because he was Luria's student. In England there
was Crick and Sydney [Brenner]. And there was us here. And that's it."</span><br />
<br />
<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">The
CSHL Library & Archives holds a number of letters between Jacob,
Watson, Brenner, Crick, and others, which illustrate the community and
friendship which existed among many of the major scientists of the era. </span><br />
<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"> </span><br />
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<table align="center" cellpadding="0" cellspacing="0" class="tr-caption-container" style="margin-left: auto; margin-right: auto; text-align: center;"><tbody>
<tr><td style="text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhaJcpAkMtUzwnnko8oh5-W3M_nxxLGr_LmnmFAdQF6EgLfLoGdmTwp9ht_1wXAMLmPs6iN7ZwTWAflVpZkmEKXxdEgtq8NnbfFYzQsFXHSfb57ZeZ-UDIsyadS5l2_UwariHhsX5SOz-Fh/s1600/Jacob+Meselson.jpg" imageanchor="1" style="margin-left: auto; margin-right: auto;"><img border="0" height="320" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhaJcpAkMtUzwnnko8oh5-W3M_nxxLGr_LmnmFAdQF6EgLfLoGdmTwp9ht_1wXAMLmPs6iN7ZwTWAflVpZkmEKXxdEgtq8NnbfFYzQsFXHSfb57ZeZ-UDIsyadS5l2_UwariHhsX5SOz-Fh/s320/Jacob+Meselson.jpg" width="250" /></a></td></tr>
<tr><td class="tr-caption" style="text-align: center;"><span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">Courtesy of the <a href="http://libgallery.cshl.edu/items/show/40970">James D. Watson Collection</a>.</span></td></tr>
</tbody></table>
<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">The letter above is from Francois Jacob to Matthew Meselson. The two, along with Sydney Brenner, conducted a famous experiment at Caltech which showed that RNA was a copy of the information in DNA. The RNA acts as a messenger, transporting the information from the nucleus to the protein-making machinery in the cell. As the letter indicates, Watson and Francois Gros were also working on RNA at the time.</span><br />
<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><br /></span>
<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">For more letters and photographs related to Francois Jacob please visit our <a href="http://libgallery.cshl.edu/items/browse/tag/Jacob%2C+Francois%2C+1920-">online repository</a>.</span>John Zarrillohttp://www.blogger.com/profile/10955424654611881866noreply@blogger.com0tag:blogger.com,1999:blog-858170159917031278.post-78229886576336020802013-03-06T06:00:00.000-05:002013-03-06T08:08:00.366-05:00CSHL Map and Bluepint Collection<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><span style="font-size: small;"><i>The
following is another post in our series highlighting the collections
that are being processed through the NHPRC Basic Processing Grant.</i></span></span><br />
<br />
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<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><span style="font-size: small;">“To put a city in a book, to put
the world on one sheet of paper -- maps are the most condensed humanized spaces
of all...They make the landscape fit indoors, make us masters of sights we
can't see and spaces we can't cover.” </span></span><br />
<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><span style="font-size: small;">― Robert Harbison, <i>Eccentric Spaces</i></span></span></div>
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<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><span style="font-size: small;"><br /></span></span></div>
<div class="MsoNormal" style="margin-bottom: .0001pt; margin-bottom: 0in; mso-layout-grid-align: none; mso-pagination: none; text-align: justify; text-autospace: none;">
<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><span style="font-size: small; line-height: 115%;">Cold
Spring Harbor Laboratory is listed on the Historic Register of Places in New
York. Our Map and Blueprint Collection is the only place to find many of the
unique maps dating from the 1890s.<span style="mso-spacerun: yes;"> </span>Even
the local historical societies do not have these maps, which represent the
history of Cold Spring Harbor Laboratory.<b style="mso-bidi-font-weight: normal;">
</b>This Collection is truly a record of the evolution of the property, buildings
and institution in its entirety. </span></span></div>
<h3 style="line-height: 115%; margin-bottom: .0001pt; margin-bottom: 0in;">
<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><span style="font-size: small; font-weight: normal; line-height: 115%;">The Cold Spring Harbor Map and
Blueprint Collection consists of topographical maps, architectural drawings,
pencil drawings, pencil sketches, and blue prints of the grounds and buildings over
the course of 140 years.</span></span></h3>
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<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><span style="font-size: small;"></span></span></div>
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<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><span style="font-size: small; line-height: 115%;">These
records have been stored on site since their creation, originally in
administrative offices under various Laboratory Directors until their removal
to the Cold Spring Harbor Laboratory Library and Archives.<span style="mso-spacerun: yes;"> </span>Most of the material designates the sibling institutions
that commissioned the work:<span style="mso-spacerun: yes;"> </span>Brooklyn
Institute of Arts and Sciences, Carnegie Institution of Washington, Long Island
Biological Association and Cold Spring Harbor Laboratory.</span></span></div>
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<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><span style="font-size: small;"><br /></span></span></div>
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<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><span style="font-size: small; line-height: 115%;">Despite their historic importance, the
storage of the Map and Blueprint Collection has been deficient. <span style="mso-spacerun: yes;"> </span>Many of the documents had foxing as seen on
this map of lands leased to the Carnegie Institute, 1908.<span style="mso-spacerun: yes;"> </span></span></span></div>
<div class="separator" style="clear: both; text-align: center;">
<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><span style="font-size: small;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEgg2VnmwTIvBagv1EieEwRdRrknYAnEa4CHk4tIMIzhNN09VN9xbWlg6ana4z4_QLWchYTILyNnPDoPYDPwi4MVBkPus9EOy5TJqfjcazkMQr1FEDrjZr2kFUDrDn8tG649yn4SJi92Mdxa/s1600/blueprint002.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="320" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEgg2VnmwTIvBagv1EieEwRdRrknYAnEa4CHk4tIMIzhNN09VN9xbWlg6ana4z4_QLWchYTILyNnPDoPYDPwi4MVBkPus9EOy5TJqfjcazkMQr1FEDrjZr2kFUDrDn8tG649yn4SJi92Mdxa/s320/blueprint002.jpg" width="221" /></a></span></span></div>
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<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><span style="font-size: small;"><br /></span></span></div>
<div class="MsoNormal" style="mso-layout-grid-align: none; mso-pagination: none; text-align: justify; text-autospace: none;">
<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><span style="font-size: small; line-height: 115%;">Others fell prey to insect damage as shown on
this 1928 rendering of the George Lane Nichols building section.</span></span></div>
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<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><span style="font-size: small;"><br /></span></span></div>
<div class="separator" style="clear: both; text-align: center;">
<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><span style="font-size: small;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEi595e4s3RZomEIiO3HyG8wY3cGMAweX-J07qRtKd3XC1jXP0qgWzVy_RHDU279EYcApjjzMiiXlwN3hQwvJkrdWm8Dtpmw7WFUwx4nlAABN1gM5z4dl6Qxd4wW9ieVFu1KdvnF8Zm8vpcI/s1600/blueprint001.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="320" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEi595e4s3RZomEIiO3HyG8wY3cGMAweX-J07qRtKd3XC1jXP0qgWzVy_RHDU279EYcApjjzMiiXlwN3hQwvJkrdWm8Dtpmw7WFUwx4nlAABN1gM5z4dl6Qxd4wW9ieVFu1KdvnF8Zm8vpcI/s320/blueprint001.jpg" width="254" /></a></span></span></div>
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<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><span style="font-size: small;"><br /></span></span></div>
<div class="MsoNormal" style="mso-layout-grid-align: none; mso-pagination: none; text-align: justify; text-autospace: none;">
<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><span style="font-size: small; line-height: 115%;">While the damage can be repaired,
it is usually disproportionally expensive to the cost of proper storage.</span></span></div>
<div class="MsoNormal" style="mso-layout-grid-align: none; mso-pagination: none; text-align: justify; text-autospace: none;">
<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><span style="font-size: small;"><br /></span></span></div>
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<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><span style="font-size: small; line-height: 115%;">Fortunately, we were able to stabilize
the entire Collection which should at least halt the progress of damage.<span style="mso-spacerun: yes;"> </span>Appropriate storage boxes, tubes and paper
were procured. Approximately 40 hours were spent boxing, wrapping and
preserving the Collection.<span style="mso-spacerun: yes;"> </span></span></span></div>
<div class="MsoNormal" style="mso-layout-grid-align: none; mso-pagination: none; text-align: justify; text-autospace: none;">
<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><span style="font-size: small; line-height: 115%;">Now that it is stabilized, this
Collection can be used with its related Collections: the Carnegie Institute of
Washington, Brooklyn Institute of Arts and Sciences, Long Island Biological
Association and Cold Spring Harbor Laboratory to study and appreciate the many aspects
of our history.<span style="mso-spacerun: yes;"> </span>On the surface, the maps
and blueprints show the physical expansion of the lab from a rural, seasonal
facility to multiple campuses larger than many universities.<span style="mso-spacerun: yes;"> </span>On closer perusal, one can see how the types
of buildings commissioned demonstrate the Lab’s changing focus from marine
biology to genetics to cancer research. Expansion, development and renovation
exploded under the leadership of Dr. Watson in 1968 and the number of prints
and blueprints post 1970 reflect this. It is our hope that now that this
Collection has the proper care and organization, it can be used to supplement
historical displays both physically and digitally.</span></span></div>
<br />
<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><span style="font-size: small;">- E.P., Project Archivist<i><br /></i></span></span>John Zarrillohttp://www.blogger.com/profile/10955424654611881866noreply@blogger.com0tag:blogger.com,1999:blog-858170159917031278.post-22245455238403138232013-03-01T15:00:00.001-05:002013-03-01T15:00:59.982-05:00DNA Letters, 1951-1953<span id="goog_1075140978"></span><span id="goog_1075140979"></span><br />
<i><span id="goog_190959264">In honor of the 60th anniversary of the discovery of the structure of DNA, we are proud to present a series of letters related to the famous discovery, all of which are housed at the CSHL Archives. Enjoy.</span></i><br />
<br />
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These letters, collected from the James D. Watson Collection
and the Francis Crick series of the Sydney Brenner Collection, tell several
stories regarding the lead up to the discovery of the double helix structure of
DNA.<span style="mso-spacerun: yes;"> </span>The letters illustrate the many difficulties
that almost prevented Watson and Crick from ever meeting, let alone
collaborating.<span style="mso-spacerun: yes;"> </span>Even after the two paired
up, trouble seemed to follow.<span style="mso-spacerun: yes;"> </span>The letters
between Crick and Maurice Wilkins illustrate the many conflicts and
personalities involved in the DNA discovery.<span style="mso-spacerun: yes;">
</span>After the discovery, letters between Milislav Demerec, Max Delbrück, and
Watson discuss the first presentation of the double helix to the world at the
1953 CSH Symposium.</div>
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<i><span id="goog_190959264"> </span></i><b style="mso-bidi-font-weight: normal;">Letter from Max Delbrück to the Chicago
Selective Service Board</b><br />
<b style="mso-bidi-font-weight: normal;">20 March 1951</b><br />
<span style="font-size: x-small;">C<span style="font-size: x-small;">o</span>urtesy of the James D. Watson Collection</span></div>
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At age 23, it was very possible that Watson could have been
drafted into the military to serve in Korea.<span style="mso-spacerun: yes;">
</span>In this letter Max Delbrück explains, “That there is no question in my
mind that it is of the national interest to permit Dr. Watson to continue his
studies and research.”<span style="mso-spacerun: yes;"> </span>Watson would
remain deferred, and was allowed to continue his scientific studies, which
eventually led him to Cambridge and Francis Crick.</div>
<br />
<div class="separator" style="clear: both; text-align: center;">
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Letter from Herman M. Kalckar to C.J. Lapp</b><br />
<b style="mso-bidi-font-weight: normal;">5 October 1951</b><br />
<span style="font-size: x-small;">C<span style="font-size: x-small;">o</span>urtesy of the James D. Watson Collection</span></div>
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After receiving his PhD from Indiana University, Watson received
a National Research Council Fellowship to study nucleic acid chemistry under
Herman M. Kalckar in Copenhagen.<span style="mso-spacerun: yes;"> </span>Watson
did not enjoy his biochemical studies, and was relieved by Kalckar’s suggestion
that he take a trip to the Zoological Station at Naples.<span style="mso-spacerun: yes;"> </span>It was here he attended Maurice Wilkin’s talk
on nucleic acids and observed an early X-ray photograph of DNA.<span style="mso-spacerun: yes;"> </span>After this talk, Watson knew he had to leave
Copenhagen and move to a laboratory that would allow him to further investigate
DNA.<span style="mso-spacerun: yes;"> </span>In this letter, Kalckar writes to
C.J. Lapp at the National Research Council encouraging him to allow Watson to
transfer to Cambridge.</div>
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Letter from Salvador Luria to James D. Watson</b><br />
<b style="mso-bidi-font-weight: normal;">20 October 1951</b><br />
<span style="font-size: x-small;">C<span style="font-size: x-small;">o</span>urtesy of the James D. Watson Collection</span></div>
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<br /></div>
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Sal Luria was crucial in getting Watson out of Copenhagen
and into Cambridge.<span style="mso-spacerun: yes;"> </span>In the summer of
1951 he met John Kendrew, who then passed on the word to Max Perutz that Watson
was interested in studying crystallography at the Cavendish. Watson soon met
with Perutz, and with Sir Lawrence Bragg’s blessing was allowed to begin work
that autumn.<span style="mso-spacerun: yes;"> </span>There was one slight
problem: Watson had failed to inform the National Research Council, who was
funding his research with a fellowship. In this letter Luria assures
Watson that he will write to the Council on Watson’s behalf.<span style="mso-spacerun: yes;"> </span>It also includes a humorous postscript
in which Luria admonishes Watson for his notoriously illegible handwriting. </div>
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<br /></div>
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Letter from Salvador Luria to Paul Weiss</b></div>
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<b style="mso-bidi-font-weight: normal;">20 October 1951</b><br />
<span style="font-size: x-small;">Courtesy of the James D. Watson Collection</span></div>
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Luria explains Watson’s situation in great detail to Paul
Weiss (chairman of the fellowship board) in an effort to allow Watson to
transfer his fellowship from Copenhagen to Cambridge.<span style="mso-spacerun: yes;"> </span>He concludes the letter by stating: “I feel
Watson’s present plan, far from being a drift into the wilderness, is a
considerate search for the type of preparation that may improve his usefulness
to biology.” How right he was.</div>
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Letter from Paul Weiss to James D. Watson</b></div>
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<b style="mso-bidi-font-weight: normal;">22 October 1951</b><br />
<span style="font-size: x-small;">C<span style="font-size: x-small;">o</span>urtesy of the James D. Watson Collection</span></div>
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Paul Weiss requests that Watson submits a statement
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Letter from James D. Watson to Paul Weiss</b></div>
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<b style="mso-bidi-font-weight: normal;">14 November 1951</b><br />
<span style="font-size: x-small;">C<span style="font-size: x-small;">o</span>urtesy of the James D. Watson Collection</span></div>
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<![endif]--> In his reply to Weiss, Watson begins with apologies, first
for leaving Copenhagen without permission, and then for ignoring the fellowship
board’s request to leave Cambridge and resume his work in Kalckar’s
laboratory.<span style="mso-spacerun: yes;"> </span>Watson quickly asserts that
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no longer any reason for him to stay.<span style="mso-spacerun: yes;"> </span>Watson
then outlines his plans: First, to work with Roy Markham on “the determination
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virus nuclear-proteins.”<span style="mso-spacerun: yes;"> </span>He justified
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structural approach is the consequence of our belief or to be honest, our
hunch, that a knowledge of the structure of nucleic acids might lead us more
directly to the mechanism of replication.”</div>
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<b style="mso-bidi-font-weight: normal;">Letter from James D. Watson to C.J. Lapp</b><br />
<b style="mso-bidi-font-weight: normal;">27 November 1951</b><br />
<span style="font-size: x-small;">Courtesy of the James D. Watson Collection</span></div>
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<span style="font-size: x-small;"><span style="font-size: small;">In this letter Watson gives a full account of his reasoning
behind leaving Copenhagen to study the structure of nucleic acids in Cambridge. Although Watson would not receive approval from
the fellowship board until January 1952, he was already in Cambridge, and had
no intension to leave. Soon he would
pair up with Francis Crick, one of the few people at Cambridge interested in
deciphering the structure of DNA. Watson
would also meet another major player in the DNA discovery, Rosalind Franklin,
who gave a talk in November 1951 outlining her research into the nucleic
acid. Crick had missed the talk, and
unfortunately Watson had misremembered some crucial technical information
regarding the water content of the DNA samples.
This would result in the construction of an incorrect model and soon
they would no longer be allowed to work on the DNA problem at all.</span></span></div>
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Letter from Maurice Wilkins to Francis Crick</b></div>
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<b style="mso-bidi-font-weight: normal;">11 December 1951</b><br />
<span style="font-size: x-small;">Courtesy of the Sydney Brenner Collection</span></div>
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In this letter Wilkins explains to Crick that the MRC
Biophysics Research Unit at King’s College had decided against Watson and
Crick’s proposal to continue research on nucleic acids.<span style="mso-spacerun: yes;"> </span>This occurred after Watson and Crick showed
their incorrect DNA model to Franklin and Wilkins.<span style="mso-spacerun: yes;"> </span>Wilkins himself preferred that both his group
at King’s and the Cavendish group continue exchanging ideas and working on the
structure of DNA, but superiors at both institutions had decided otherwise.<span style="mso-spacerun: yes;"> </span></div>
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Letter from Maurice Wilkins to Francis Crick</b></div>
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<b style="mso-bidi-font-weight: normal;">11 December 1951</b><br />
<span style="font-size: x-small;">Courtesy of the Sydney Brenner Collection</span></div>
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approved by John Randall, the Director of the MRC Biophysics Research Unit, and
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</span>In this letter Wilkins describes the opposition of Randall to the
collaboration and his own attempts to mediate the problem.<span style="mso-spacerun: yes;"> </span>Wilkins was ultimately unsuccessful, and it
would be over a year until Watson and Crick were once again allowed to work on
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</span><b style="mso-bidi-font-weight: normal;">Letter from Crick and Watson to Maurice Wilkins</b><br />
<span style="font-size: small;"><b>13 December 1951</b></span><br />
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Courtesy of the Sydney Brenner Collection</span></div>
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Watson and Crick sent back a heavily edited letter to
Wilkins.<span style="mso-spacerun: yes;"> </span>There is a striking difference
between the attitudes of the two parties.<span style="mso-spacerun: yes;">
</span>As Alexander Gann and Jan Witkowski explain in their Nature paper on the
Crick-Wilkins letters, “the agonized tone of Wilkins’s letters and the cavalier
ring of Watson and Crick’s reply, even at this low point for the Cambridge team
. . . [was a] reminder that the group at King’s was already divided and
dysfunctional.”</div>
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<b style="mso-bidi-font-weight: normal;">Letter from Maurice Wilkins to Francis Crick</b></div>
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<b style="mso-bidi-font-weight: normal;">January 1953</b><br />
<span style="font-size: x-small;">Courtesy of the Sydney Brenner Collection</span></div>
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Several events unfolded in early 1953 that set Watson and
Crick on the path to deciphering the structure of DNA.<span style="mso-spacerun: yes;"> </span>Linus Pauling’s manuscript describing the
incorrect “triple helix” was being circulated and Watson brought the paper to
London to show Wilkins and Franklin.<span style="mso-spacerun: yes;"> </span>It
was during this visit that Wilkins showed Watson the famous X-ray diffraction
“Photograph 51” of B-form DNA, which clearly demonstrated a helical structure.<span style="mso-spacerun: yes;"> </span></div>
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In this letter, Wilkins discusses an upcoming talk by
Franklin, which Watson and Crick are eager to attend.<span style="mso-spacerun: yes;"> </span>Unfortunately, they were barred from the
discussion because it was closed to external visitors.<span style="mso-spacerun: yes;"> </span>They would arrive two days after the talk
(and after Franklin had departed King’s to join J.D. Bernal’s group at Birkbeck
College), and finally see Photograph 51 for the first time.<span style="mso-spacerun: yes;"> </span>Lawrence Bragg, eager to beat Pauling to the
discovery, finally allowed Watson and Crick to devote their time to DNA.<span style="mso-spacerun: yes;"> </span>Soon they would construct their famous double
helix model.</div>
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<div class="separator" style="clear: both; text-align: center;">
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<b style="mso-bidi-font-weight: normal;">Letter from Max
Delbrück to James D. Watson<br />
17 April 1953</b><br />
<span style="font-size: x-small;">Courtesy of the James D. Watson Collection</span><br />
<br />
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Max Delbrück states that he is trying get Watson an
invitation to the 1953 CSH Symposium on Viruses to present the DNA structure.<span style="mso-spacerun: yes;"> </span>He also notes that Alexander Rich has an
X-ray photograph of DNA that is just as good as King’s College’s.</div>
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<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEgID2JTe6OuXxnNHeJGeZWXFSiDkNO_X3NHgMtU_yFyX3T3dNXAU7AFPObdmKIE25Y-IimwFvLGT_VGmb5mEsfT76dlazm3uHTrfx3rJbHzswGuCSd4GUKn6xuZrGwyMx6-utdMTEdoPSJR/s1600/Demerec+letter.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="320" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEgID2JTe6OuXxnNHeJGeZWXFSiDkNO_X3NHgMtU_yFyX3T3dNXAU7AFPObdmKIE25Y-IimwFvLGT_VGmb5mEsfT76dlazm3uHTrfx3rJbHzswGuCSd4GUKn6xuZrGwyMx6-utdMTEdoPSJR/s320/Demerec+letter.jpg" width="247" /></a></div>
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<b style="mso-bidi-font-weight: normal;">Letter from Milislav
Demerec to James D. Watson<br />
27 April 1953</b><br />
Courtesy of the James D. Watson Collection</div>
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1 May 1953<br />
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In this letter Delbrück explains that, “You are invited
because I swore (and Pauling seconded my oath…) that the Watson-Crick DNA
structure is of basic importance in connection with at least half a dozen of
the principle papers to be given at the Symposium.”</div>
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<b style="mso-bidi-font-weight: normal;">Letter from Max
Delbrück to James D. Watson<br />
12 May 1953<br />
</b><span style="font-size: x-small;">Courtesy of the James D. Watson Collection</span></div>
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Delbrück gives his opinion on the double helix structure of
DNA.</div>
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<b style="mso-bidi-font-weight: normal;">Photograph of Watson
presenting the double helix at the 1953 CSH Symposium on Viruses.<br />
June 1953<br />
</b><span style="font-size: x-small;">Courtesy of the James D. Watson Collection</span></div>
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<span id="goog_190959265"></span>John Zarrillohttp://www.blogger.com/profile/10955424654611881866noreply@blogger.com0tag:blogger.com,1999:blog-858170159917031278.post-19161181778423929572013-02-27T09:43:00.001-05:002013-02-27T09:43:26.629-05:00Banbury Reports Collection<!--[if gte mso 9]><xml>
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<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><i>The
following is another post in our series highlighting the collections
that are being processed through the NHPRC Basic Processing Grant.</i> </span></div>
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<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">In 1976, Charles Sammis Robertson, who lived in Lloyd
Harbor, about 5 miles from Cold Spring Harbor Laboratory, gave his estate on
Banbury Lane, together with an endowment for its upkeep, to the Cold Spring
Harbor Lab for use as a conference center. <span style="mso-spacerun: yes;"></span>This postcard,<span style="mso-spacerun: yes;">
</span>incorporating a photo taken by R. Meurer<span style="mso-spacerun: yes;">,
</span>captures the Charles Sammis
Robertson House looking towards Coopers Bluff.<span style="mso-spacerun: yes;"> </span><span style="mso-spacerun: yes;"> </span></span></div>
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<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEiO2SHjPbUsvF-qKdwGTUJj-p-r7jZyKsBeRWr0Yqok4s0TVgZsKbTd7a920jk71CoWo-jjUeXPFkaL0k0a4ZoicB7Eo5R6ZpRePIG7z2q-5u-hwcSLYYWOe81IkIDx_H88Zhv1O09ZBYnI/s1600/banbury+photo+01.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="202" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEiO2SHjPbUsvF-qKdwGTUJj-p-r7jZyKsBeRWr0Yqok4s0TVgZsKbTd7a920jk71CoWo-jjUeXPFkaL0k0a4ZoicB7Eo5R6ZpRePIG7z2q-5u-hwcSLYYWOe81IkIDx_H88Zhv1O09ZBYnI/s320/banbury+photo+01.jpg" width="320" /></a></span></div>
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<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">Since 1978 the
Banbury Center has been the site of competitive and <span style="mso-spacerun: yes;"> </span>intensive courses as well as international
meetings on topics in biology, biomedical topics and theoretical biology.<span style="mso-spacerun: yes;"> </span>The Center holds workshop-discussion style
meetings on topics in almost every area of modern experimental biology and on
important policy issues. <span style="mso-spacerun: yes;"></span>The Banbury
Report Collection consists of manuscripts, transcripts, publisher’s galleys,
reprints, and correspondence with various authors and program notes relating to
science-related meetings held at the Banbury Center.<span style="mso-spacerun: yes;"> </span>These materials were used in conjunction
with the publication of the Banbury Reports by the Cold Spring Harbor Press.</span></div>
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<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">- E.P., Project Archivist </span></div>
John Zarrillohttp://www.blogger.com/profile/10955424654611881866noreply@blogger.com0tag:blogger.com,1999:blog-858170159917031278.post-41225878932859164202013-01-28T15:53:00.000-05:002013-02-27T10:22:35.496-05:00An Ode to Bacteriophage Lambda<div class="separator" style="clear: both; text-align: center;">
<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEiwciYafIkPRuN0S5O6HSDUig8AYFNGIDl0lilAYHmj_jmdN3QWCULhwGNEJ1eFZjrRAKsjt_piUn-pf1UCVsP0eQeD4-a09olShWM5SKf7ux15m68QQMkK2fAsncDuWEyZ_7Sj4uNzd-wn/s1600/JDW_02_02_1555_044.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="271" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEiwciYafIkPRuN0S5O6HSDUig8AYFNGIDl0lilAYHmj_jmdN3QWCULhwGNEJ1eFZjrRAKsjt_piUn-pf1UCVsP0eQeD4-a09olShWM5SKf7ux15m68QQMkK2fAsncDuWEyZ_7Sj4uNzd-wn/s320/JDW_02_02_1555_044.jpg" width="320" /></a></div>
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<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">Poem by Richard O. Roblin III, who was a student of James D. Watson at Harvard University in the mid to late 1960s.</span><br />
<span style="font-size: small;"><span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><br /></span></span>
<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">Digitized as part of the "</span><span style="font-size: small;"><span>Codebreakers: Makers of Modern Genetics</span>" project.</span> </span>John Zarrillohttp://www.blogger.com/profile/10955424654611881866noreply@blogger.com0tag:blogger.com,1999:blog-858170159917031278.post-32006839412466340112013-01-11T09:03:00.000-05:002013-02-27T10:23:10.629-05:00Watson on The War on Cancer<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">Dr. Watson has been in the <a href="http://www.reuters.com/article/2013/01/09/us-usa-cancer-watson-idUSBRE90805N20130109" target="_blank">news</a> again lately after publishing a paper in the Royal Society's journal <a href="http://rsob.royalsocietypublishing.org/content/3/1/120144.full" target="_blank">Open Biology</a>. In the paper Watson questions the benefits of anti-oxidants and criticizes the U.S.'s current "war on cancer."</span><br />
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<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">This type of thing is really old hat for Watson, who has been a blunt critic of the way we have been funding cancer research since the 1970s, when he served on the National Cancer Advisory Board. In March of 1975 he gave a speech at the dedication of the Seeley G. Mudd Building at MIT which also drew national headlines.</span><br />
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<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEijQ564-CHKjDI8lNF4Xd4wJeou_e1fdZu7kbHnoJ9J2ZtgZ6SbYiwWkfmCH8foQyo0_VuZnEgAtdLdn37Eo4vJFTK52v2LVOFPVgCASesMgxbH0OI1vCwa90IeiXBoRNCltMgmMHeWEs_L/s1600/JDW_02_02_1522_105.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="311" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEijQ564-CHKjDI8lNF4Xd4wJeou_e1fdZu7kbHnoJ9J2ZtgZ6SbYiwWkfmCH8foQyo0_VuZnEgAtdLdn37Eo4vJFTK52v2LVOFPVgCASesMgxbH0OI1vCwa90IeiXBoRNCltMgmMHeWEs_L/s320/JDW_02_02_1522_105.jpg" width="320" /></a></span></div>
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<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">Watson was quickly inundated with letters from both scientists and the public, many whom agreed that we were not making enough progress with the the cancer problem. One letter in particular caught my attention with a hypothesis that I believe has been completely overlooked in the ensuing years:</span><br />
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<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEiOAV2cCTkCHtehqgTQayc92ZS-WhI1m8zW8hQ7GtDRRi_PC-FjgL8nFoNNoapyGCVAxd_3p75CdzP8YYrAVKBrf3o4zf6pHqbXAJExUdeqvz_RvCY6X6oHVz1TcWaCl4Wlb4-xb1PUq725/s1600/JDW_02_02_1522_099.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="142" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEiOAV2cCTkCHtehqgTQayc92ZS-WhI1m8zW8hQ7GtDRRi_PC-FjgL8nFoNNoapyGCVAxd_3p75CdzP8YYrAVKBrf3o4zf6pHqbXAJExUdeqvz_RvCY6X6oHVz1TcWaCl4Wlb4-xb1PUq725/s400/JDW_02_02_1522_099.jpg" width="400" /></a></span></div>
John Zarrillohttp://www.blogger.com/profile/10955424654611881866noreply@blogger.com0tag:blogger.com,1999:blog-858170159917031278.post-44290398256022990472013-01-03T09:37:00.001-05:002013-02-27T10:23:34.202-05:00From One Nobel Prize Winner to Another<div class="separator" style="clear: both; text-align: center;">
<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEgQVY0WKjb3fWhqoo4KMFSGIUrWwEKXMcUdW4lr5nEaQXB6otUgOKibdt1BS1jgKKAKrb4MNTBLDyK9mMWT9tZGxwSAq2dbYxhDoknirjI4wUhuexw-q4i5scppHD4B1aJexKaToMTgxhzc/s1600/JDW_02_02_1516_080.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="320" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEgQVY0WKjb3fWhqoo4KMFSGIUrWwEKXMcUdW4lr5nEaQXB6otUgOKibdt1BS1jgKKAKrb4MNTBLDyK9mMWT9tZGxwSAq2dbYxhDoknirjI4wUhuexw-q4i5scppHD4B1aJexKaToMTgxhzc/s320/JDW_02_02_1516_080.jpg" width="250" /></a></span></div>
<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><br />Ever since Dr. Watson won his Nobel Prize in 1962 people have been seeking his autograph. As part of our digitization project, I'm creating metadata for these autograph requests and I'm plugging names into the Library of Congress Name Authority File to see if anyone of interest pops up. I often wonder if the people who wrote to Watson later went on to achieve anything of note themselves. </span><br />
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<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">Well this morning I typed "Agre, Peter" into the search engine and was pleasantly surprised to find that Peter was in fact a fellow Nobel Prize winner. Agre, who received the 2003 Nobel Prize in Chemistry for the discovery of aquaporins, wrote to Watson in 1970 while he was studying medicine at Jones Hopkins. Peter praised Watson for his work on The Molecular Biology of the Gene, and thanked him sending an autographed photo, which was now hanging up next to Pete's two other idols, Albert Einstein and Linus Pauling. He concludes with the letter with, "I will always be grateful and inspired." </span><br />
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<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">I can't help but imagine that some future Nobel Prize winner has written (or tweeted) Agre himself -- and that in 50 years or so some archivist will be as amused by these connections as me.</span>John Zarrillohttp://www.blogger.com/profile/10955424654611881866noreply@blogger.com0tag:blogger.com,1999:blog-858170159917031278.post-79968886795420298722012-12-21T12:06:00.000-05:002013-02-27T10:26:12.344-05:00Early Impressions of The Double Helix<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">One thing that I have learned about Dr. Watson as a writer is that he is not shy about sharing unfinished drafts with colleagues. We have scores of letters from the likes of Paul Doty, Tom Maniatis, and Matt Meselson commenting on early versions of Avoid Boring People. He also famously shared drafts of The Double Helix with Crick and Wilkins, who were, somewhat understandingly, appalled.</span><span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><br /></span>
<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><br /></span>
<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">As part of the "<span style="font-size: small;">Codebreakers: Makers of Modern Genetics"</span> digitization project, we will soon be making these letters freely available online for the first time.</span><br />
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<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">I found one particular set of letters regarding an early draft of The Double Helix very interesting. Watson had sent a copy of the manuscript to an acquaintance in the summer of 1965, who subsequently sent a series of letters back to Watson documenting her delight with the draft. Her name was Suzanne Reeder, had just left Cambridge (Massachusetts), and was obviously close with Watson. The letters start in July 1965. She mentions attending a conference in Berlin, as well as meeting Odile Crick in Cambridge sometime earlier, before returning home to England. Towards the end of the letter she indicates that she will be flying back to the states, and then asks for a copy of the book.</span><br />
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<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">Watson apparently swore Suzanne to secrecy -- he clearly knew that the book would be controversial.</span><br />
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<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">Her initial impressions of Crick are quite positive: "You make Francis sound tremendous -- he gets better as one reads on."</span><br />
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<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEheOjLgtRzIaaqbId7AIX_8lU7WVFwFNVs60_oBuLsVDon7eZbLngFQNckWSBzdZj2Fna41O1yJKw7heA9n7_D8ffw6dI5XOSZ9flJJHHKASp13AyBJZhxD0ZbdPpFdhqcZXi_Du-fLTVph/s1600/SUZ3.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="168" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEheOjLgtRzIaaqbId7AIX_8lU7WVFwFNVs60_oBuLsVDon7eZbLngFQNckWSBzdZj2Fna41O1yJKw7heA9n7_D8ffw6dI5XOSZ9flJJHHKASp13AyBJZhxD0ZbdPpFdhqcZXi_Du-fLTVph/s320/SUZ3.jpg" width="320" /></a></span></div>
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<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">Suzanne anticipates that Watson will have trouble publishing the memoir: "What a pity you can't print it as written."</span><br />
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<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">She was also acquainted with Walter Gilbert, and discusses problems with his repressor research below. "I shall be quite sad to think of all his work unrewarded -- all those sleepless hours in the cold room." He was rewarded, about 25 years later, with a Nobel Prize.</span><br />
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<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">Her impressions of Crick clearly change as the book progresses: "The more I read, the more I think Francis must just be horrifying. I sewed a piece of his dressing gown [presumably a memento from her meeting with Odile] into my quilt yesterday and I think that's as close as I'd want to get to him"</span><br />
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<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">She also mentions Watson's great success with his other famous work, the Molecular Biology of the Gene. Watson tends to work on multiple projects at the same time. Both MBotG and The Double Helix were written in the early 1960s. Genes, Girls, and Gamow and Avoid Boring People were both written throughout the 1990s and early 2000s. When he assumed the directorship of Cold Spring Harbor Laboratory he remained a professor at Harvard, and he served as head of the U.S. Human Genome Project while still leading CSHL.</span><br />
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<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">She didn't get to read the finished work in 1965. Watson was traveling across Africa meeting with local scientists and giving lectures for the Ford Foundation, and did not have time to complete the manuscript as of yet. Suzanne ends the letters prophetically: "I am absolutely certain that the book contains libel - which is tragic, since the libelous bits are so hilarious. I hope the lawyer doesn't mutilate it too much."</span><br />
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<br />John Zarrillohttp://www.blogger.com/profile/10955424654611881866noreply@blogger.com0tag:blogger.com,1999:blog-858170159917031278.post-15021492765796505902012-11-19T09:27:00.001-05:002012-11-19T09:28:33.122-05:00Cold Spring Harbor Audio Visual Collection <!--[if gte mso 9]><xml>
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<![endif]--><span style="font-size: small;"><span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><span style="line-height: 115%;">Processing the Cold Spring Harbor Audio Visual Collection was a unique
experience due to the volume and scope of the Collection. The Collection
overall consists of 4,950 pieces of media, in 11 different formats and takes up
about 130 linear feet of shelf space, depending how you count it. It was
grouped by format but hadn’t been looked at in years, which meant that old
inventory lists, if they existed, were no longer accurate. I had to start over cataloguing the media
which took about 165 hours. Keeping the
Collection grouped by media made sense on one level (as opposed to grouping by
subject matter) because much of the media was not readable and the processing
often became a game of “Name that obsolete Format”. Below is a photograph of the Analog Video Formats. </span></span></span><br />
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<br />
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<br />
<div class="MsoNormal" style="margin-bottom: 0in;">
<span style="font-size: small;"><span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">I learned that at the time of
recording the formats were considered state of the art. Now we, as an Archive, are unable to read or
view what is on the tapes. eBay is full of players and recording devices and
there are blogs which lament the demise of the Hi-8 tape. But the lessons ring through loud and
clear. We as Archivists prepare Disaster
Plans to prevent and manage threats to our collection. Typical threats are leaky pipes, electrical
shorts and poor storage climates. </span></span></div>
<div class="MsoNormal" style="margin-bottom: 0in;">
<span style="font-size: small;"><span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><br /></span></span></div>
<div class="MsoNormal" style="margin-bottom: 0in;">
<span style="font-size: small;"><span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">But isn’t the real threat to our collection
the possibility of losing our information?
Behold the Type C Helical Film Reel and let us go forth and regularly
assess our formats for compatibility and retrieval.</span></span></div>
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<span style="font-size: small;"><span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><br /></span></span></div>
<div class="separator" style="clear: both; text-align: center;">
<span style="font-size: small;"><span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjwlGuxX7Sps50vRTThpTPtizdFGAaDIGWXmBbN7ZDxhclLQSa7aHFx627MoN-HZYhoPoIbMP9VKhOHuz8TOX7ma3_6pfUUdXUnorvUj3sIzBuR3MPyvb1vtx8eWV37AOe77GnqfKRhcLbe/s1600/Type+C+Helical+Video.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="185" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjwlGuxX7Sps50vRTThpTPtizdFGAaDIGWXmBbN7ZDxhclLQSa7aHFx627MoN-HZYhoPoIbMP9VKhOHuz8TOX7ma3_6pfUUdXUnorvUj3sIzBuR3MPyvb1vtx8eWV37AOe77GnqfKRhcLbe/s320/Type+C+Helical+Video.jpg" width="320" /></a></span></span></div>
<div class="MsoNormal" style="margin-bottom: 0in;">
<span style="font-size: small;"><span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">- Amy Driscoll, Project Archivist</span></span></div>
John Zarrillohttp://www.blogger.com/profile/10955424654611881866noreply@blogger.com0tag:blogger.com,1999:blog-858170159917031278.post-46934890943339271752012-11-14T13:51:00.000-05:002013-02-27T10:27:01.316-05:00Codebreakers: Makers of Modern Genetics Preview on Flickr<div class="separator" style="clear: both; text-align: center;">
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<span style="font-family: "Helvetica Neue", Arial, Helvetica, sans-serif;">For t<span style="font-size: small;">he past year we have been digitizing documents from the James D. Watson and Sydney Brenner Collections as part of the Wellcome Library's "<span>Codebreakers: Makers of Modern Genetics</span>" project. This includes all types of documents: letters, postcards, handwritten manuscripts, laboratory data,</span> and even Watson's day calendars. But the images I was most interested in come from Watson's extensive photograph collection. </span><br />
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<span style="font-family: "Helvetica Neue", Arial, Helvetica, sans-serif;">The photos document Watson's entire life, from his infancy to his 80s. In fact, they go back even further -- the portrait above is of his father, James D. Watson, Sr., and was taken in 1897. Take a closer look at the photograph and you will notice that little Jimmy is not seated on a chair, but is actually on his mother's lap! Taking portraits was a much lengthier procedure in the 19th century, so mothers often hid beneath a sheet to comfort their children and keep them still throughout the photo session. The result is a slightly unsettling image of an infant held by a cloaked specter (known as "ghost mothers").</span><br />
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<span style="font-family: "Helvetica Neue", Arial, Helvetica, sans-serif;">For more early images from the Watson Collection check out our <span style="font-family: "Helvetica Neue", Arial, Helvetica, sans-serif;"><span style="font-family: "Helvetica Neue", Arial, Helvetica, sans-serif;"><a href="http://www.flickr.com/photos/cshlarchives/" target="_blank">Flickr page</a></span></span> where we will be providing a preview of the photographs digitized as part of <span style="font-family: "Helvetica Neue", Arial, Helvetica, sans-serif;">"</span></span><span style="font-family: "Helvetica Neue", Arial, Helvetica, sans-serif;"><span style="font-family: "Helvetica Neue", Arial, Helvetica, sans-serif;"><span style="font-family: "Helvetica Neue", Arial, Helvetica, sans-serif;"><span style="font-size: small;"><span>Codebreakers: Makers of Modern Genetics</span></span></span>" project.</span></span>John Zarrillohttp://www.blogger.com/profile/10955424654611881866noreply@blogger.com0tag:blogger.com,1999:blog-858170159917031278.post-38112703529307416372012-11-05T14:11:00.000-05:002012-11-05T14:11:16.390-05:00Hurricane Sandy and the NEH Preservation Assistance Grant<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">When word came that a hurricane was moving up the eastern seaboard and would soon wreak certain havoc all along the coast, we were prepared. Our library is located directly on the Long Island Sound, so flood preparation plans were already in place. The bottom shelf of our storage space is set several inches off the floor, but to be safe everything on those shelves were moved to designated safe rooms on the upper level of the library. Our archives are also equipped with a storm door, a heavy iron door which can be bolted into place in case of emergencies. It was locked tight by Sunday afternoon. Luckily the archives remained dry throughout the storm, but if the worst case scenario had occurred, our disaster recovery plan provides us with the policies and procedures to effectively respond to the emergency. All of the above was made possible with guidance provided by the NEH Preservation Assistance Grant.</span><br />
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<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">In early 2011 we were awarded the NEH grant, which provided funding for a two day preservation assessment by consultant Tom Clareson (of <a href="http://www.lyrasis.org/" target="_blank">LYRASIS</a>). The weeks prior to his visit were spent reviewing the preservation policies and disaster plans of other institutions, and in an effort to not appear completely clueless, we drafted a disaster plan of our own. Tom was happy to review our draft policies, and with his recommendations we finalized the disaster recovery plan that served us so well during the recent storm.</span><br />
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<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">Tom also helped with our environmental monitoring program. Although we have control over our archive's HVAC system, and generally maintain a consistent temperature and relative humidity, we had no way accurately logging the hour-to-hour environment of the archives. In the past we had simply recorded the temperature and RH of our storage room </span><span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"> by hand in a notebook, </span>once in the morning and once in the afternoon. Then we would compile that information in a spreadsheet at the end of the month. This gave us only two readings a day, and no record of the environment over weekends and holidays. Tom recommended the purchase of a <a href="https://www.imagepermanenceinstitute.org/environmental/pem2-datalogger" target="_blank">PEM2 datalogger</a>, which were are produced by the Image Permanence Institute. This is a very simple and effective way to monitor your archives. The device essentially runs on its own. Once a week we plug in a USB drive into the monitor and the data that has been accruing then automatically transfers to the drive. The data can then be exported into spreadsheets or uploaded online into IPI's online climate notebook. The devices are easy to use, relatively affordable ($349 a unit), and highly recommended.</span><br />
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<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">After the preservation assessment Tom provided us with a detailed report of his visit. It covered everything from environmental conditions and storage, to media migration and digital preservation. We were able to quickly respond to many of his recommendations: these included the aforementioned environmental monitors, moving records off the floor (to the shelves where space allowed), moving maps from hanging files to flat storage, and the purchase of stronger bookends to prevent slumping in our Rare Book Room. He was also very helpful in terms of future preservation funding by alerting us to a number of additional preservation grants from a variety of government offices.</span><br />
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<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">In September 2011 Tom returned to conduct a preservation workshop at our library. The talk was open to the public and was attended by a number of librarians and archivists from the New York metropolitan area, as well as many library and archives graduate students.</span><br />
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<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">Overall, the <span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">NEH Preservation Assistance Grant proved crucial to protecting our collections, which survived the most catastrophic storm we have seen in many years. With our preservation and disaster response policies in place I am confident that they will remain safe and sound (and dry), despite their close proximity to the sea.</span></span><br />
<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><br /></span>John Zarrillohttp://www.blogger.com/profile/10955424654611881866noreply@blogger.com0tag:blogger.com,1999:blog-858170159917031278.post-60113130371219881472012-10-18T14:06:00.001-04:002012-10-18T14:13:09.600-04:0050 Years Ago Today: Watson Wins Nobel Prize<div class="separator" style="clear: both; text-align: center;">
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On this day 50 years ago it was announced that Francis Crick, Maurice Wilkins, and James D. Watson had won the <a href="http://www.nobelprize.org/nobel_prizes/medicine/laureates/1962/" target="_blank">1962 Nobel Prize for Physiology or Medicine</a> for the discovery of the double helix structure of DNA. Watson was a professor at Harvard University at the time, and a student took the liberty of announcing the news by scrawling "Dr. Watson has just won the Nobel Prize!" on his classroom blackboard. Here's a humorous side-note regarding Harvard and the prize: Watson assumed that he would receive receive a large bonus from Harvard on top of the standard $2,000 a year raise. The university, restricted by budget cuts, instead opted to not give out any pay raises at all. Watson was not amused.<br />
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Next year marks another milestone for Watson: the 60th anniversary of the actual discovery. And there's no better way to join in on the celebration than purchasing a copy of The Annotated and Illustrated Double Helix! This brand new edition is packed with original documents and a plethora of never-before-seen photographs of all the major players from the time of the discovery, many of which are courtesy of the CSHL Library and Archives. Sample chapters of the new edition are available for your perusal at the <a href="http://www.cshlpress.com/default.tpl?cart=135058018649560126&fromlink=T&linkaction=full&linksortby=oop_title&--eqSKUdatarq=947" target="_blank">CSHL Press website</a>.John Zarrillohttp://www.blogger.com/profile/10955424654611881866noreply@blogger.com0tag:blogger.com,1999:blog-858170159917031278.post-87725778087035797682012-10-17T14:44:00.001-04:002012-10-17T14:44:55.672-04:00Watson returns to Italy<div class="separator" style="clear: both; text-align: center;">
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Above is a newsclip of Dr. Watson that aired this past weekend in Italy. At age 84 he is still traversing the globe, delivering lectures on his famous discovery, as well as his current scientific passion, the future of cancer research. Watson has a long-time connection with Italy. Salvador Luria was Watson's mentor at the University of Indiana and introduced the young graduate student to the wold of phage research. That would lead Watson to his first summer at Cold Spring Harbor, where he remains to this day. It was at Indiana that he met another famous Italian scientist, Renato Dulbecco. Dulbecco would go on to work with Joseph Sambrook at the Salk Institute in the late 1960s, who would then go on to be Watson's Assistant Director at CSHL for almost 20 years. These type of connections abound in the scientific world.<br />
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<span style="font-size: x-small;">Manny Delbruck and Salvador Luria at CSHL in 1953</span></div>
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In April 1951 Watson traveled to Italy for the first time, to spend two months at the Zoological Station at Naples. It was here that Watson took in a talk by Maurice Wilkins on the structure of DNA. Towards the end of his talk he presented a new X-ray photograph of DNA -- this fateful image would prove to Watson that the nucleic acid had a regular structure, and therefore the structure could be deciphered using the standard methods: a combination of X-ray crystallography and/or model building. The wheels started turning in his brain, and two years later he and Francis Crick (with much needed insight from Rosalind Franklin's famous X-ray photograph) "discovered" the helical structure of DNA -- and unraveled the "secret of life."<br />
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This time around Watson only stayed a few days in Lo Stivale, delivering 3 talks before flying off to Cyprus. And the never ending lecture tour continues...</div>
John Zarrillohttp://www.blogger.com/profile/10955424654611881866noreply@blogger.com0tag:blogger.com,1999:blog-858170159917031278.post-75227056053264071392012-09-10T08:53:00.000-04:002012-09-10T08:55:36.574-04:00The Cold Spring Harbor Clippings Collection<div class="MsoNormal" style="margin-bottom: .0001pt; margin-bottom: 0in;">
<span style="font-family: "Helvetica Neue", Arial, Helvetica, sans-serif;"><i>The
following is another post in our series highlighting the collections
that are being processed through the NHPRC Basic Processing Grant.</i></span></div>
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<span style="font-family: "Arial","sans-serif";">The Cold Spring Harbor Clippings
Collection is a compilation of newspapers, magazines and trade journals
relating to the scientists and events both at CSHL and the scientific community
at large.<span style="mso-spacerun: yes;"> </span>The Collection dates from
1903-2012.<span style="mso-spacerun: yes;"> </span>From 1924, if not earlier, CSHL
or the Biological Laboratory, as we were then known, employed a clipping
service to keep track of newsworthy mentions.<span style="mso-spacerun: yes;">
</span>Answering the age old question, “Which came first the chicken or the
egg?” was certainly a top story.</span></div>
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</xml><![endif]--> Note the two newspapers here: The <i style="mso-bidi-font-style: normal;">Torrington Connecticut Register</i> and the <i style="mso-bidi-font-style: normal;">Worcester Massachusetts Post</i>. <span class="st">The Torrington Register is now out of commission and is replaced by </span><i><span style="font-family: "Arial","sans-serif";">Register</span></i><span class="st"> Citizen
which covers Litchfield County and regional Northwest </span><i><span style="font-family: "Arial","sans-serif";">CT</span></i><span class="st"> news, <span style="mso-bidi-font-weight: bold;">including Torrington.</span> The </span><i style="mso-bidi-font-style: normal;">Worcester Massachusetts Post</i> (actually
the Worcester Evening Post) expired in 1938.<span style="mso-spacerun: yes;">
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<span style="font-family: "Arial","sans-serif";">Discoveries and inventions were
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<span style="font-family: "Arial","sans-serif";">Other early obituaries of note were: William
Henry Nichols, Walter Jennings and Reginald Harris.</span></div>
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<br /></div>
<div class="MsoNormal" style="line-height: normal; mso-margin-bottom-alt: auto; mso-margin-top-alt: auto;">
<span style="font-family: "Arial","sans-serif";">Some of the
more interesting finds in the Clipping Collection were not so much what was
clipped or saved but from whence they came.<span style="mso-spacerun: yes;">
</span>When possible I noted the newspaper cited.<span style="mso-spacerun: yes;"> </span>This showed the wide breadth of the Lab’s
outreach, notable for the pre-internet, pre-television days.</span></div>
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<span style="font-family: "Arial","sans-serif";">A student of
Long Island Suburban History could use these files to track the growth and
decline of the small town newspaper.<span style="mso-spacerun: yes;">
</span>Today, many of those smaller newspapers have either closed or merged
with a neighboring town’s press.<span style="mso-spacerun: yes;"> </span>In
addition, publishing groups have bought up many of the local papers and created
“families” such as the Anton Community Newspapers <i style="mso-bidi-font-style: normal;">(</i></span><a href="http://www.antonnews.com/farmingdaleobserver.html"><i style="mso-bidi-font-style: normal;"><span style="color: windowtext; font-family: "Arial","sans-serif"; text-decoration: none; text-underline: none;">Farmingdale Observer</span></i></a><i style="mso-bidi-font-style: normal;"><span style="font-family: "Arial","sans-serif";">,
</span></i><a href="http://www.antonnews.com/floralparkdispatch.html"><i style="mso-bidi-font-style: normal;"><span style="color: windowtext; font-family: "Arial","sans-serif"; text-decoration: none; text-underline: none;">Floral Park Dispatch</span></i></a><i style="mso-bidi-font-style: normal;"><span style="font-family: "Arial","sans-serif";">,
</span></i><a href="http://www.antonnews.com/gardencitylife.html"><i style="mso-bidi-font-style: normal;"><span style="color: windowtext; font-family: "Arial","sans-serif"; text-decoration: none; text-underline: none;">Garden City Life</span></i></a><i style="mso-bidi-font-style: normal;"><span style="font-family: "Arial","sans-serif";">,
</span></i><a href="http://www.antonnews.com/glencoverecordpilot.html"><i style="mso-bidi-font-style: normal;"><span style="color: windowtext; font-family: "Arial","sans-serif"; text-decoration: none; text-underline: none;">Glen Cove Record
Pilot</span></i></a><i style="mso-bidi-font-style: normal;"><span style="font-family: "Arial","sans-serif";">, </span></i><a href="http://greatneckrecord.com/" target="_blank"><i style="mso-bidi-font-style: normal;"><span style="color: windowtext; font-family: "Arial","sans-serif"; text-decoration: none; text-underline: none;">Great Neck Record</span></i></a><i style="mso-bidi-font-style: normal;"><span style="font-family: "Arial","sans-serif";">,
</span></i><a href="http://www.antonnews.com/hicksvilleillustratednews.html"><i style="mso-bidi-font-style: normal;"><span style="color: windowtext; font-family: "Arial","sans-serif"; text-decoration: none; text-underline: none;">Hicksville
Illustrated News</span></i></a><i style="mso-bidi-font-style: normal;"><span style="font-family: "Arial","sans-serif";">, </span></i><a href="http://www.antonnews.com/levittowntribune.html"><i style="mso-bidi-font-style: normal;"><span style="color: windowtext; font-family: "Arial","sans-serif"; text-decoration: none; text-underline: none;">Levittown Tribune</span></i></a><i style="mso-bidi-font-style: normal;"><span style="font-family: "Arial","sans-serif";">,
</span></i><a href="http://manhasset-press.com/" target="_blank"><i style="mso-bidi-font-style: normal;"><span style="color: windowtext; font-family: "Arial","sans-serif"; text-decoration: none; text-underline: none;">Manhasset Press</span></i></a><i style="mso-bidi-font-style: normal;"><span style="font-family: "Arial","sans-serif";">,
</span></i><a href="http://www.antonnews.com/massapequanobserver.html"><i style="mso-bidi-font-style: normal;"><span style="color: windowtext; font-family: "Arial","sans-serif"; text-decoration: none; text-underline: none;">Massapequan Observer</span></i></a><i style="mso-bidi-font-style: normal;"><span style="font-family: "Arial","sans-serif";">,
</span></i><a href="http://www.antonnews.com/mineolaamerican.html"><i style="mso-bidi-font-style: normal;"><span style="color: windowtext; font-family: "Arial","sans-serif"; text-decoration: none; text-underline: none;">Mineola American</span></i></a><i style="mso-bidi-font-style: normal;"><span style="font-family: "Arial","sans-serif";">,
</span></i><a href="http://www.antonnews.com/illustratednews.html"><i style="mso-bidi-font-style: normal;"><span style="color: windowtext; font-family: "Arial","sans-serif"; text-decoration: none; text-underline: none;">New Hyde Park
Illustrated News</span></i></a><i style="mso-bidi-font-style: normal;"><span style="font-family: "Arial","sans-serif";">, </span></i><a href="http://www.antonnews.com/oysterbayenterprisepilot.html"><i style="mso-bidi-font-style: normal;"><span style="color: windowtext; font-family: "Arial","sans-serif"; text-decoration: none; text-underline: none;">Oyster Bay Enterprise-Pilot</span></i></a><i style="mso-bidi-font-style: normal;"><span style="font-family: "Arial","sans-serif";">,
</span></i><a href="http://www.antonnews.com/plainviewoldbethpageherald.html"><i style="mso-bidi-font-style: normal;"><span style="color: windowtext; font-family: "Arial","sans-serif"; text-decoration: none; text-underline: none;">Plainview-Old
Bethpage Herald</span></i></a><i style="mso-bidi-font-style: normal;"><span style="font-family: "Arial","sans-serif";">, </span></i><a href="http://portwashington-news.com/" target="_blank"><i style="mso-bidi-font-style: normal;"><span style="color: windowtext; font-family: "Arial","sans-serif"; text-decoration: none; text-underline: none;">Port Washington News</span></i></a><i style="mso-bidi-font-style: normal;"><span style="font-family: "Arial","sans-serif";">,
</span></i><a href="http://theroslynnews.com/" target="_blank"><i style="mso-bidi-font-style: normal;"><span style="color: windowtext; font-family: "Arial","sans-serif"; text-decoration: none; text-underline: none;">The Roslyn News</span></i></a><i style="mso-bidi-font-style: normal;"><span style="font-family: "Arial","sans-serif";">,
</span></i><a href="http://www.antonnews.com/syossetjerichotribune.html"><i style="mso-bidi-font-style: normal;"><span style="color: windowtext; font-family: "Arial","sans-serif"; text-decoration: none; text-underline: none;">Syosset-Jericho
Tribune</span></i></a><i style="mso-bidi-font-style: normal;"><span style="font-family: "Arial","sans-serif";">, </span></i><a href="http://www.antonnews.com/threevillagetimes.html"><i style="mso-bidi-font-style: normal;"><span style="color: windowtext; font-family: "Arial","sans-serif"; text-decoration: none; text-underline: none;">Three Village Times</span></i></a><i style="mso-bidi-font-style: normal;"><span style="font-family: "Arial","sans-serif";">,
</span></i><a href="http://www.antonnews.com/westburytimes.html"><i style="mso-bidi-font-style: normal;"><span style="color: windowtext; font-family: "Arial","sans-serif"; text-decoration: none; text-underline: none;">The Westbury Times</span></i></a><span style="font-family: "Arial","sans-serif";">) and the Herald Community Newspapers
(</span><i style="mso-bidi-font-style: normal;"><span style="font-family: "Arial","sans-serif"; mso-fareast-font-family: "Times New Roman";">Baldwin, </span></i><a href="https://www.liherald.com/bellmore/"><i style="mso-bidi-font-style: normal;"><span style="color: windowtext; font-family: "Arial","sans-serif"; mso-fareast-font-family: "Times New Roman"; text-decoration: none; text-underline: none;">Bellmore</span></i></a><i style="mso-bidi-font-style: normal;"><span style="font-family: "Arial","sans-serif"; mso-fareast-font-family: "Times New Roman";">, </span></i><a href="https://www.liherald.com/eastmeadow/"><i style="mso-bidi-font-style: normal;"><span style="color: windowtext; font-family: "Arial","sans-serif"; mso-fareast-font-family: "Times New Roman"; text-decoration: none; text-underline: none;">East Meadow</span></i></a><i style="mso-bidi-font-style: normal;"><span style="font-family: "Arial","sans-serif"; mso-fareast-font-family: "Times New Roman";">, </span></i><a href="https://www.liherald.com/eastrockaway/"><i style="mso-bidi-font-style: normal;"><span style="color: windowtext; font-family: "Arial","sans-serif"; mso-fareast-font-family: "Times New Roman"; text-decoration: none; text-underline: none;">East
Rockaway</span></i></a><i style="mso-bidi-font-style: normal;"><span style="font-family: "Arial","sans-serif"; mso-fareast-font-family: "Times New Roman";">,
</span></i><a href="https://www.liherald.com/elmont/"><i style="mso-bidi-font-style: normal;"><span style="color: windowtext; font-family: "Arial","sans-serif"; mso-fareast-font-family: "Times New Roman"; text-decoration: none; text-underline: none;">Elmont</span></i></a><i style="mso-bidi-font-style: normal;"><span style="font-family: "Arial","sans-serif"; mso-fareast-font-family: "Times New Roman";">, </span></i><a href="https://www.liherald.com/fivetowns/"><i style="mso-bidi-font-style: normal;"><span style="color: windowtext; font-family: "Arial","sans-serif"; mso-fareast-font-family: "Times New Roman"; text-decoration: none; text-underline: none;">Five Towns</span></i></a><i style="mso-bidi-font-style: normal;"><span style="font-family: "Arial","sans-serif"; mso-fareast-font-family: "Times New Roman";">, </span></i><a href="https://www.liherald.com/franklinsquare/"><i style="mso-bidi-font-style: normal;"><span style="color: windowtext; font-family: "Arial","sans-serif"; mso-fareast-font-family: "Times New Roman"; text-decoration: none; text-underline: none;">Franklin
Square</span></i></a><i style="mso-bidi-font-style: normal;"><span style="font-family: "Arial","sans-serif"; mso-fareast-font-family: "Times New Roman";">,
</span></i><a href="https://www.liherald.com/islandpark/"><i style="mso-bidi-font-style: normal;"><span style="color: windowtext; font-family: "Arial","sans-serif"; mso-fareast-font-family: "Times New Roman"; text-decoration: none; text-underline: none;">Island
Park</span></i></a><i style="mso-bidi-font-style: normal;"><span style="font-family: "Arial","sans-serif"; mso-fareast-font-family: "Times New Roman";">,
</span></i><a href="https://www.liherald.com/longbeach/"><i style="mso-bidi-font-style: normal;"><span style="color: windowtext; font-family: "Arial","sans-serif"; mso-fareast-font-family: "Times New Roman"; text-decoration: none; text-underline: none;">Long
Beach</span></i></a><i style="mso-bidi-font-style: normal;"><span style="font-family: "Arial","sans-serif"; mso-fareast-font-family: "Times New Roman";">,
</span></i><a href="https://www.liherald.com/lynbrook/"><i style="mso-bidi-font-style: normal;"><span style="color: windowtext; font-family: "Arial","sans-serif"; mso-fareast-font-family: "Times New Roman"; text-decoration: none; text-underline: none;">Lynbrook</span></i></a><i style="mso-bidi-font-style: normal;"><span style="font-family: "Arial","sans-serif"; mso-fareast-font-family: "Times New Roman";">, </span></i><a href="https://www.liherald.com/malverne/"><i style="mso-bidi-font-style: normal;"><span style="color: windowtext; font-family: "Arial","sans-serif"; mso-fareast-font-family: "Times New Roman"; text-decoration: none; text-underline: none;">Malverne</span></i></a><i style="mso-bidi-font-style: normal;"><span style="font-family: "Arial","sans-serif"; mso-fareast-font-family: "Times New Roman";">, </span></i><a href="https://www.liherald.com/merrick/"><i style="mso-bidi-font-style: normal;"><span style="color: windowtext; font-family: "Arial","sans-serif"; mso-fareast-font-family: "Times New Roman"; text-decoration: none; text-underline: none;">Merrick</span></i></a><i style="mso-bidi-font-style: normal;"><span style="font-family: "Arial","sans-serif"; mso-fareast-font-family: "Times New Roman";">, </span></i><a href="https://www.liherald.com/oceanside/"><i style="mso-bidi-font-style: normal;"><span style="color: windowtext; font-family: "Arial","sans-serif"; mso-fareast-font-family: "Times New Roman"; text-decoration: none; text-underline: none;">Oceanside</span></i></a><i style="mso-bidi-font-style: normal;"><span style="font-family: "Arial","sans-serif"; mso-fareast-font-family: "Times New Roman";">, </span></i><a href="https://www.liherald.com/rockvillecentre/"><i style="mso-bidi-font-style: normal;"><span style="color: windowtext; font-family: "Arial","sans-serif"; mso-fareast-font-family: "Times New Roman"; text-decoration: none; text-underline: none;">Rockville
Centre</span></i></a><i style="mso-bidi-font-style: normal;"><span style="font-family: "Arial","sans-serif"; mso-fareast-font-family: "Times New Roman";">,
</span></i><a href="https://www.liherald.com/valleystream/"><i style="mso-bidi-font-style: normal;"><span style="color: windowtext; font-family: "Arial","sans-serif"; mso-fareast-font-family: "Times New Roman"; text-decoration: none; text-underline: none;">Valley Stream</span></i></a><i style="mso-bidi-font-style: normal;"><span style="font-family: "Arial","sans-serif"; mso-fareast-font-family: "Times New Roman";">, </span></i><a href="https://www.liherald.com/westhempstead/"><i style="mso-bidi-font-style: normal;"><span style="color: windowtext; font-family: "Arial","sans-serif"; mso-fareast-font-family: "Times New Roman"; text-decoration: none; text-underline: none;">West
Hempstead</span></i></a><span style="font-family: "Times New Roman","serif"; mso-fareast-font-family: "Times New Roman";">)<span style="mso-spacerun: yes;">. </span></span></div>
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<span style="font-family: "Arial","sans-serif"; mso-fareast-font-family: "Times New Roman";">Whether an independent newspaper such as the <i style="mso-bidi-font-style: normal;">Locust Valley Leader</i>,</span><span style="font-family: "Arial","sans-serif";"> or part of a conglomerate such as
Richner Communications which owns the Herald Community Newspapers listed above as
well as the <i style="mso-bidi-font-style: normal;">Oyster Bay Guardian</i>, what
they all have in common is the lack of an indexed searchable archive.<span style="mso-spacerun: yes;"> </span>A few newspapers are available at local
libraries on microfilm, but most are not. A researcher does not have any way of
searching through past issues other than prevailing upon the altruistic nature
of the publisher to manually go through the stacks.<span style="mso-spacerun: yes;"> </span>Therefore, the Clippings Collection becomes
extremely important in studying the local events in CSHL history such as the community
conflict over the widening of Route 25A and the proposed Lab building expansion
plans in the late 1990s.<span style="mso-spacerun: yes;"> </span>The situation
and extenuating circumstances were not widely covered by Newsday and the New
York Times (n.b. the Newsday Archive only goes back until 1985 although the
paper has been in published since 1940).<span style="mso-spacerun: yes;">
</span>The Clippings Collection is the only substantial record of those events
and it cannot be reconstructed through on-line sources. </span></div>
<div class="MsoNormal" style="line-height: normal; mso-margin-bottom-alt: auto; mso-margin-top-alt: auto;">
<br /></div>
<div class="MsoNormal" style="line-height: normal; mso-margin-bottom-alt: auto; mso-margin-top-alt: auto;">
<span style="font-family: "Arial","sans-serif";">At this
time, the Clipping Collection dwindles through the 2000s and peters out with a
few clippings in 2011 and one article for 2012.<span style="mso-spacerun: yes;">
</span>Given the above circumstances of no searchable local news archive for
the foreseeable future, I recommend that the Archives maintain a collection of
local newspapers. <span style="mso-spacerun: yes;"> </span>Newspapers to include
are: <i style="mso-bidi-font-style: normal;">Huntington News, Locust Valley
Leader</i>, <i style="mso-bidi-font-style: normal;">Long Islander</i>, <i style="mso-bidi-font-style: normal;">Oyster Bay Enterprise Pilot</i>, and the <i style="mso-bidi-font-style: normal;">Oyster Bay Guardian</i>.</span></div>
<div class="MsoNormal" style="line-height: normal; mso-margin-bottom-alt: auto; mso-margin-top-alt: auto;">
<br /></div>
<div class="MsoNormal" style="line-height: normal; mso-margin-bottom-alt: auto; mso-margin-top-alt: auto;">
<span style="font-family: "Arial","sans-serif";">Below is a
list of New York Newspapers found in this collection:</span></div>
<div class="MsoNormal" style="line-height: normal; mso-margin-bottom-alt: auto; mso-margin-top-alt: auto;">
<br /></div>
<div class="MsoNormalCxSpMiddle" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in; mso-add-space: auto;">
<span style="font-family: "Arial","sans-serif";">Adirondack
Daily Enterprise</span></div>
<div class="MsoNormalCxSpMiddle">
<span style="font-family: "Arial","sans-serif";">Albany
NY Times Union</span></div>
<div class="MsoNormalCxSpMiddle">
<span style="font-family: "Arial","sans-serif";">Amityville
Record</span></div>
<div class="MsoNormalCxSpMiddle" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in; mso-add-space: auto;">
<span style="font-family: "Arial","sans-serif";">Ardsley,
NY Sun</span></div>
<div class="MsoNormalCxSpMiddle" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in; mso-add-space: auto;">
<span style="font-family: "Arial","sans-serif";">Babylon
NY Beacon; </span></div>
<div class="MsoNormalCxSpMiddle" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in; mso-add-space: auto;">
<span style="font-family: "Arial","sans-serif";">Bayshore
NY Suffolk</span></div>
<div class="MsoNormalCxSpMiddle" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in; mso-add-space: auto;">
<span style="font-family: "Arial","sans-serif";">Bethpage
Tribune</span></div>
<div class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in;">
<span style="font-family: "Arial","sans-serif";">Brooklyn Eagle</span></div>
<div class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in;">
<span style="font-family: "Arial","sans-serif";">Brooklyn Standard Union</span></div>
<div class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in;">
<span style="font-family: "Arial","sans-serif";">Cloversville, NY Leader</span></div>
<div class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in;">
<span style="font-family: "Arial","sans-serif";">Farmingdale Observer</span></div>
<div class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in;">
<span style="font-family: "Arial","sans-serif";">Floral Park NY Gateway</span></div>
<div class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in;">
<span style="font-family: "Arial","sans-serif";">Garden City News</span></div>
<div class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in;">
<span style="font-family: "Arial","sans-serif";">Great Neck News</span></div>
<div class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in;">
<span style="font-family: "Arial","sans-serif";">Haverstraw NY Messenger</span></div>
<div class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in;">
<span style="font-family: "Arial","sans-serif";">Huntington NY Bulletin</span></div>
<div class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in;">
<span style="font-family: "Arial","sans-serif";">Independent Voice
Oceanside NY</span></div>
<div class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in;">
<span style="font-family: "Arial","sans-serif";">Irvington NY Gazette</span></div>
<div class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in;">
<span style="font-family: "Arial","sans-serif";">Jamaica NY Press</span></div>
<div class="MsoNormal" style="margin-bottom: .0001pt; margin-bottom: 0in;">
<span style="font-family: "Arial","sans-serif";">Locust Valley Leader</span></div>
<div class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in;">
<span style="font-family: "Arial","sans-serif";">Long Islander</span></div>
<div class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in;">
<span style="font-family: "Arial","sans-serif";">Malverne NY Herald</span></div>
<div class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in;">
<span style="font-family: "Arial","sans-serif";">Massapequa Post</span></div>
<div class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in;">
<span style="font-family: "Arial","sans-serif";">Mineola American</span></div>
<div class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in;">
<span style="font-family: "Arial","sans-serif";">Mt. Vernon NY Argus</span></div>
<div class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in;">
<span style="font-family: "Arial","sans-serif";">New York American</span></div>
<div class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in;">
<span style="font-family: "Arial","sans-serif";">NYC American</span></div>
<div class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in;">
<span style="font-family: "Arial","sans-serif";">NYC North Side News</span></div>
<div class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in;">
<span style="font-family: "Arial","sans-serif";">NYC Oil Reporter</span></div>
<div class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in;">
<span style="font-family: "Arial","sans-serif";">NYC World</span></div>
<div class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in;">
<span style="font-family: "Arial","sans-serif";">New York Herald</span></div>
<div class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in;">
<span style="font-family: "Arial","sans-serif";">New York Sun</span></div>
<div class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in;">
<span style="font-family: "Arial","sans-serif";">New York Telegram</span></div>
<div class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in;">
<span style="font-family: "Arial","sans-serif";">New York Times</span></div>
<div class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in;">
<span style="font-family: "Arial","sans-serif";">Noticias Del Mundo NYC </span></div>
<div class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in;">
<span style="font-family: "Arial","sans-serif";">Olean NY Herald</span></div>
<div class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in;">
<span style="font-family: "Arial","sans-serif";">Oyster Bay Enterprise</span></div>
<div class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in;">
<span style="font-family: "Arial","sans-serif";">Oyster Bay Pilot</span></div>
<div class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in;">
<span style="font-family: "Arial","sans-serif";">Patchogue NY News</span></div>
<div class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in;">
<span style="font-family: "Arial","sans-serif";">Pleasantville NY Journal</span></div>
<div class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in;">
<span style="font-family: "Arial","sans-serif";">South Shore Tribune</span></div>
<div class="MsoNormalCxSpMiddle" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in; mso-add-space: auto;">
<span style="font-family: "Arial","sans-serif";">Suffolk
Bulletin</span></div>
<div class="MsoNormalCxSpMiddle" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in; mso-add-space: auto;">
<span style="font-family: "Arial","sans-serif";">Utica
NY Dispatch</span></div>
<div class="MsoNormalCxSpMiddle">
<span style="font-family: "Arial","sans-serif";">Wall
Street Journal</span></div>
<div class="MsoNormalCxSpMiddle" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in; mso-add-space: auto;">
<span style="font-family: "Arial","sans-serif";">Westbury
Times</span></div>
<div class="MsoNormalCxSpMiddle" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in; mso-add-space: auto;">
<span style="font-family: "Arial","sans-serif";">White
Plains NY Republican</span></div>
<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><br /></span>
<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">- Amy Driscoll, Project Archivist</span><br />
<div class="MsoNormal" style="margin-bottom: .0001pt; margin-bottom: 0in;">
<span style="font-family: "Arial","sans-serif";">
</span></div>
<span style="font-family: "Helvetica Neue", Arial, Helvetica, sans-serif;"><i></i></span>John Zarrillohttp://www.blogger.com/profile/10955424654611881866noreply@blogger.com0tag:blogger.com,1999:blog-858170159917031278.post-66401152805958482232012-09-06T09:12:00.000-04:002012-09-06T10:38:21.944-04:00Science Books That Changed The World<div class="separator" style="clear: both; text-align: center;">
<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjpIWgjK5DebKz4o2tz2yip2DJ7rn8IRysVQ2Q4zJQTWzIaQevV87LWCfCUVD5fvqTQHfikgT1ckT4CltSTeeQxlHie3TwqTWuUR9X7hyphenhyphentHOXU54pv-Ub-9AbcouUsrKNALZAO78FeEg9SE/s1600/Was+ist+Leben+(1)-OG.JPG" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="246" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjpIWgjK5DebKz4o2tz2yip2DJ7rn8IRysVQ2Q4zJQTWzIaQevV87LWCfCUVD5fvqTQHfikgT1ckT4CltSTeeQxlHie3TwqTWuUR9X7hyphenhyphentHOXU54pv-Ub-9AbcouUsrKNALZAO78FeEg9SE/s320/Was+ist+Leben+(1)-OG.JPG" width="320" /></a></div>
<br />
<span style="font-family: "Helvetica Neue", Arial, Helvetica, sans-serif;"><a href="http://www.newscientist.com/blogs/culturelab/2012/08/what-popular-science-books-changed-the-world.html?cmpid=EMC|NSNS|2012-3008-GLOBAL-books&utm_medium=EMC&utm_source=NSNS&utm_campaign=books" target="_blank">New Scientist online</a> is currently holding a competition to determine what is the most influential popular science book of all-time. 25 titles have been shortlisted by the journal, including Dr. Watson's famous memoir, <i>The Double Helix</i>. The list compiles many of the most famous publications of the past three centuries, including <i>On the Origin of Species</i>, <i>The Selfish Gene</i>, and <i>A Brief History of Time</i>. There are, however, some notable books left off the list, such as Carl Sagan's <i>Cosmos</i>, and a personal favorite, <i>Surely You're Joking, Mr, Feynman! </i>It should be noted that Watson himself would almost certainly choose Erwin Schrödinger's <i>What is Life?</i>, which inspired him to change his studies from ornithology to genetics, and set him on a path to the discovery of the double helix structure of DNA.</span><br />
<span style="font-family: "Helvetica Neue", Arial, Helvetica, sans-serif;"><br /></span>
<span style="font-family: "Helvetica Neue", Arial, Helvetica, sans-serif; font-size: x-small;">Image courtesy of the <span style="font-family: Arial, Helvetica;">the<a href="http://www.zbp.univie.ac.at/schrodinger/euebersicht.htm" target="_blank"> Central Library for Physics in Vienna</a></span></span><span style="font-family: "Helvetica Neue", Arial, Helvetica, sans-serif;">.</span>John Zarrillohttp://www.blogger.com/profile/10955424654611881866noreply@blogger.com0tag:blogger.com,1999:blog-858170159917031278.post-26200234157689884282012-08-31T09:57:00.000-04:002012-08-31T10:43:36.091-04:00Winship Herr Collection <span style="font-family: "Helvetica Neue", Arial, Helvetica, sans-serif;"><i>The following is another post in our series highlighting the collections that are being processed through the NHPRC Basic Processing Grant.</i></span><br />
<span style="font-family: "Helvetica Neue", Arial, Helvetica, sans-serif;"></span><br />
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<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjzwzCfumHkBUwjmRefEok-YfTZ910WNtuEwJkB7zB6Nsag7CAhVHM-ZTWtpN8JQvhMzUgIHsaYLS13RVmvIWIyKmJ06nnanMUHf3tdba5nvaJB6uzHUNKSferRc_BAhep9WHHtVzYuiIEP/s1600/Photo1.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="320" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjzwzCfumHkBUwjmRefEok-YfTZ910WNtuEwJkB7zB6Nsag7CAhVHM-ZTWtpN8JQvhMzUgIHsaYLS13RVmvIWIyKmJ06nnanMUHf3tdba5nvaJB6uzHUNKSferRc_BAhep9WHHtVzYuiIEP/s320/Photo1.jpg" width="283" /></a></div>
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<span style="font-family: "Helvetica Neue", Arial, Helvetica, sans-serif;">Winship Herr was born in 1958 in New Haven, CT. In 1974, he obtained his A.B. (Biology) at University of California at Santa Cruz and received his PhD from Harvard University in 1982 for studies on recombinant retroviruses in leukemogenic mice with Walter Gilbert. After postdoctoral studies with Frederick Sanger in Cambridge, England and then with Joe Sambrook at Cold Spring Harbor Laboratory, he joined the CSHL faculty in 1984. After achieving the rank of Senior Scientist, he served as assistant director of the Laboratory from 1994-2002 and from 1998-2004 was the founding Dean of the Watson School of Biological Sciences, a doctoral degree-granting school. In 2004, he joined the Center for Integrative Genetics in Lausanne, Switzerland.</span><br />
<span style="font-family: "Helvetica Neue", Arial, Helvetica, sans-serif;"></span><br />
<span style="font-family: "Helvetica Neue", Arial, Helvetica, sans-serif;">The Winship Herr Collection is comprised mainly of material generated from 1991 to 1994. At CSHL, Dr. Herr’s work focused on the mechanics of transcriptional regulation in eukaryotes utilizing two cellular proteins, Oct-1 and Oct-2 and a herpes simplex protein, VP16.</span><br />
<br />
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<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhDQDKntehlaHQuxqF1oVT1FzHzW4Mv0MTleMvV3iEtsjXjaK7-fGN0S5sq_hNuy9xmNtOSq_f57mOE71vryQmd61puGOXht3csjk6nxb1CRefIfHbE6D_B9fZ8qYtfl6mpdVrYUgEuxBgQ/s1600/Photo2.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="221" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhDQDKntehlaHQuxqF1oVT1FzHzW4Mv0MTleMvV3iEtsjXjaK7-fGN0S5sq_hNuy9xmNtOSq_f57mOE71vryQmd61puGOXht3csjk6nxb1CRefIfHbE6D_B9fZ8qYtfl6mpdVrYUgEuxBgQ/s320/Photo2.jpg" width="320" /></a></div>
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<span style="font-family: Arial; font-size: x-small;">(Winship Herr, Craig Hinkley, Michelle Cleary, Betty Lee, Bill Tansey - 1993)</span></div>
<span style="font-family: "Helvetica Neue", Arial, Helvetica, sans-serif;"></span><br />
<span style="font-family: "Helvetica Neue", Arial, Helvetica, sans-serif;">Dr. Herr’s work is clearly sophisticated and his methodology as meticulous and thorough as one would expect from an esteemed senior scientist and his lab at CSHL. </span><br />
<span style="font-family: "Helvetica Neue", Arial, Helvetica, sans-serif;"></span><br />
<span style="font-family: "Helvetica Neue", Arial, Helvetica, sans-serif;">However, even the best scientists cannot predict when inspiration strikes and must use whatever is at hand to record their findings. Seen here is a note on the Oct-1 and Oct-2 proteins, written on an everyday paper towel. </span><br />
<span style="font-family: Arial;"></span><br />
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<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhxP3vb4HRkYWEWpCG0543ZVjmPbceiPj-qZ5lSwcii8ah1hU9Droj2WzwjLLlWWlgMxAknnLkA785sD4rl-VcaXZXTA5ncCpiJRTmi6hHEQpf7k9w8r1EgRX4X1KntAAfGoOARp0XLrNmR/s1600/Herr+Paper+Towel+Note+Pad.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="240" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhxP3vb4HRkYWEWpCG0543ZVjmPbceiPj-qZ5lSwcii8ah1hU9Droj2WzwjLLlWWlgMxAknnLkA785sD4rl-VcaXZXTA5ncCpiJRTmi6hHEQpf7k9w8r1EgRX4X1KntAAfGoOARp0XLrNmR/s320/Herr+Paper+Towel+Note+Pad.jpg" width="320" /></a></div>
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<span style="font-family: "Helvetica Neue", Arial, Helvetica, sans-serif;">- Amy Driscoll, Project Archivist</span></div>
John Zarrillohttp://www.blogger.com/profile/10955424654611881866noreply@blogger.com0tag:blogger.com,1999:blog-858170159917031278.post-83908327590657758972012-08-20T15:31:00.000-04:002013-02-27T10:27:47.897-05:001968: A Banner Year for Watson<div class="separator" style="clear: both; text-align: center;">
<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhl5IeUjy-ZKwMl37uYg2JxSqd5YvHpYVnT8dZL7s2ZubJ7AvZCAoArtovPRGm4c1RvWKXJGgfb5mhzL15aj0ZpnJPm2lokpXIQHVefHdKf4xmo24gPnozBcIAs-O_pfBSJloYyH0FkCHMj/s1600/langridge+letter.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="320" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhl5IeUjy-ZKwMl37uYg2JxSqd5YvHpYVnT8dZL7s2ZubJ7AvZCAoArtovPRGm4c1RvWKXJGgfb5mhzL15aj0ZpnJPm2lokpXIQHVefHdKf4xmo24gPnozBcIAs-O_pfBSJloYyH0FkCHMj/s320/langridge+letter.jpg" width="248" /></a></div>
<div style="text-align: center;">
<span style="font-size: x-small;">Letter from Robert Langridge to Watson <br />congratulating him on the three major events of 1968</span></div>
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<br />
<span style="font-family: "Helvetica Neue", Arial, Helvetica, sans-serif;">1968 was a momentous year in the life of James D. Watson, perhaps only eclipsed by 1953, the year of his famous co-discovery. Coincidentally, three major events occurred during the year, each of which would shape the course of his life to come. </span><br />
<br />
<span style="font-family: "Helvetica Neue", Arial, Helvetica, sans-serif;">First, his personal account of the discovery of the structure of DNA was published and became a surprise bestseller. Watson had been interested in writing for much of his life (influenced by his mother and father, both avid readers), and he viewed the success of his memoir as one of his great accomplishments. As of 2012, he has written a number of non-fiction works, including a sequel to his 1968 memoir (<i>Genes, Girls, and Gamow</i>).</span><br />
<br />
<span style="font-family: "Helvetica Neue", Arial, Helvetica, sans-serif;">1968 was also the year that Watson took over as Director of Cold Spring Harbor Laboratory. It's former director, John Cairns, had almost single-handily saved the lab from certain financial doom during his brief tenure in the mid-1960s. While its finances had been stabilized, it was up to Watson to drum up enough money to rehabilitate the lab's facilities and hire a new generation of scientists to work on the new major problems in biology. It was Watson who decided the research focus of the lab should be cancer and with grant money flowing from the "War on Cancer" he was able (with the help of Joseph Sambrook) to build new laboratories and initiate a tumor virus program to rival any other research institution. It was here, on the north shore of Long Island, that Watson honed his skills as a spokesman and fundraiser for scientific research.</span><br />
<br />
<span style="font-family: Arial;">Finally, it was also the year of his marriage to Elizabeth Lewis. Watson had famously remained a bachelor until well into his late-30s, despite all efforts find the perfect bride. He was rewarded for his patience, and has been happily married ever since. The couple still live on campus at CSHL in their residence "Ballybung."</span>John Zarrillohttp://www.blogger.com/profile/10955424654611881866noreply@blogger.com0tag:blogger.com,1999:blog-858170159917031278.post-4164729392729174142012-07-31T13:34:00.001-04:002012-08-03T08:51:22.636-04:00Amos Avery Photographic Collection<br />
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<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEh6QvD53-wwTfuUMlk7Fo1oPVlG3XxuOQxDkokWFMImgeVTQO_vylRLim2KCOvtnK9HYsLJLCBVkB8iXyhBhXenawCsX6kFX0mIoTsUe4t_Pjjo-58scZ12dyQtPYwVEtLZdU5sG2BI_G93/s1600/Datura+Workers+1927.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="215" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEh6QvD53-wwTfuUMlk7Fo1oPVlG3XxuOQxDkokWFMImgeVTQO_vylRLim2KCOvtnK9HYsLJLCBVkB8iXyhBhXenawCsX6kFX0mIoTsUe4t_Pjjo-58scZ12dyQtPYwVEtLZdU5sG2BI_G93/s320/Datura+Workers+1927.jpg" width="320" /></a></div>
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<span style="font-size: x-small; line-height: 115%;">Datura Workers at CSH, 1927 (Avery is seated on the left)</span></center>
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<span style="font-size: small;"></span><br />
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<span style="font-size: small; line-height: 115%;">Amos Avery
was an associate in plant breeding for the Carnegie Institution of Washington
Department of Genetics (predecessor of the CSHL). Mr. Avery was in charge of
the gardens and greenhouses under Dr. Albert Blakeslee (center in the photo above) from 1926-42. He left
Cold Spring Harbor in 1943. During this time Mr. Avery and his wife Ruth took
hundreds of photographs in and around the Carnegie campus at Cold Spring
Harbor, NY. This collection, now housed in the CSHL Archives, includes 129
unsorted photographs, approximately 75 negatives, and 3 scrapbooks.<br /><br /> </span></div>
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<span style="font-size: small; line-height: 115%;">The photos
were given to the Archives by Mr. Avery’s daughter, Nancy Avery in April 1999,
shortly after his death. It was accessioned and processed by Clare Clark and
Brian Soldo, by a grant provided by the New York State’s Documentary Heritage
Program (DHP), a statewide program ensures the survival of New York's
documentary heritage by providing financial support and guidance to the
not-for-profit organizations that hold, collect and make available the state's
historical records. </span></div>
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<span style="font-size: small;"><br /></span><br />
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<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEgojrFZXCK8oOmwxSXFy-A1rSeU7FR8Uy2zvXtOeHOyfAxwheNvSsAGLm6OSWhhkGmooKa9_ofWKNp95hBnzR8PHya14JQTqcWvh2vgZ-t2ZH-ZTZBr1O9XEaYLC1aLEJQPIVSNCo-kIh1T/s1600/Avery+Blog+Image.JPG" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="236" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEgojrFZXCK8oOmwxSXFy-A1rSeU7FR8Uy2zvXtOeHOyfAxwheNvSsAGLm6OSWhhkGmooKa9_ofWKNp95hBnzR8PHya14JQTqcWvh2vgZ-t2ZH-ZTZBr1O9XEaYLC1aLEJQPIVSNCo-kIh1T/s320/Avery+Blog+Image.JPG" width="320" /></a></div>
<div style="text-align: center;">
<span style="font-size: small;"><span style="font-size: x-small;">A page from an Avery scrapbook -- the "Carnegie" building in the top right photograph is now the CSHL Library.</span></span></div>
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<span style="font-size: small;"><br /></span></div>
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<span style="font-size: small;"></span></div>
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<div class="MsoNormal" style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">
<span style="font-size: small; line-height: 115%;">The majority
of the Avery’ photos are from the 1930s, and the collection gives a view of
the scientific and personal lives of scientists within the early days of the
Department of Genetics of the Carnegie Institution of Washington at Cold Spring
Harbor. It will also be of interest to anyone interested in Long Island history
of that era, and includes images of the Roosevelt Field airfield, Otto Kahn’s
Oheka estate, and Walt Whitman’s birthplace. The scrapbooks contain detailed
captions. An interesting photograph caption says “Charles Lindberg comes to
visit…", however, the image is so small it’s virtually unrecognizable. </span><br />
<span style="font-size: small;"><br /></span><br />
<span style="font-size: small; line-height: 115%;">- Brian Soldo, DHP Grant Intern</span></div>John Zarrillohttp://www.blogger.com/profile/10955424654611881866noreply@blogger.com0tag:blogger.com,1999:blog-858170159917031278.post-71655065351107818712012-07-30T08:51:00.001-04:002012-07-30T08:51:38.200-04:00Press Release: Grant from NYS Documentary Heritage Program makes possible basic processing of CSHL’s “hidden collections”<div style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">
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<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">The Library & Archives of Cold
Spring Harbor Laboratory (CSHL) has received a 2011-2012 Documentary Heritage
Program (DHP) grant for “Arrangement and Description of the Hidden Collections
of Cold Spring Harbor Laboratory’s Legacy Institutions, 1890-1974.” </span>
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The amount is $ 17,034 and was awarded as part of the DHP’s
mission to ensure the survival of historical records documenting economic
change in New York
State during the 20th and
21st centuries.</div>
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The records pertinent to the grant belong to the entities representing
the contemporary Laboratory’s predecessor institutions, and span the period
1890-1974. The project also has provided for basic processing of three personal
collections that offer further insight into the work and daily lives of
scientists at the Laboratory during that time; and for processing of the collection
of the Eugenics Record Office (ERO), which existed at Cold Spring
Harbor from 1910 to 1944.</div>
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The collections are currently available via CSHL’s online
Digital Collections Database (http://archives.cshl.edu/) and online catalog,
and will be available through the New York State Archives’ Historical Document
Inventory (Archives Grid), as well as other union catalogs (National Union
Catalog of Manuscripts <a href="http://www.loc.gov/coll/nucmc/index.html">http://www.loc.gov/coll/nucmc/index.html</a>)
and digital repositories, according to Mila Pollock, Executive Director of the
CSHL Library & Archives and project director of this effort.<span style="mso-spacerun: yes;"> </span></div>
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“The entire CSHL community and other users of these and
related CSHL Archives collections will learn more about the origins and history
of CSHL, and recognize the value of these collections in documenting the
history of science education and research at CSHL and its connection to New York State’s bioscience industry in the 20th
and 21st centuries,” Pollock says. </div>
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Here is a more detailed description of the collections whose
processing has been made possible by the DHP grant award:</div>
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<b style="mso-bidi-font-weight: normal;">The Brooklyn
Institute of Arts and Sciences’ Biological Laboratory Collection</b></div>
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This collection documents the
Brooklyn Institute of Arts and Sciences’ investment in the marine biological
laboratory at Cold Spring Harbor,
NY, and its evolution from a
summer school for biology teachers into a dedicated scientific research
laboratory. The collection contains photographs, letters, student lists, Board
of Trustees minutes, Directors’ reports, booklets, annual reports, student
registration cards, and fundraising records. </div>
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<b style="mso-bidi-font-weight: normal;">The LIBA Biological
Laboratory Collection</b></div>
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In 1924, the Brooklyn Institute of
Arts and Sciences withdrew its support and a group of wealthy neighbors took up
the cause to sustain science education and research at the Long Island
Biological Association (LIBA) Biological Laboratory. This collection contains
correspondence, minutes of the Board of Directors, administrative
correspondence files, photographs, research files, employment records and
financial ledgers.</div>
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<b style="mso-bidi-font-weight: normal;">The Carnegie
Institution of Washington
Station for Experimental Evolution; The Department of Genetics; and The
Genetics Research Unit Collection<span style="mso-spacerun: yes;"> </span></b></div>
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In 1904, the Carnegie Institution
of Washington established the Station for Experimental Evolution at Cold Spring
Harbor. It was this
research facility that later merged with the Biological Laboratory to form Cold
Spring Harbor Laboratory. This collection contains extensive correspondence
files, institutional administrative files, photographs, lantern slides,
financial ledgers, employment records, and research files. </div>
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<b style="mso-bidi-font-weight: normal;">Eugenics Record
Office (ERO) Collection</b></div>
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This collection includes
correspondence, documents, photographs, journals, and books from 1910 to 1944, the
period during which there was a Eugenics Record Office at Cold Spring
Harbor, supported by the
Carnegie Institution of Washington. The ERO played a dubious, but significant,
role in the social history of the United States. Thus it is important
that the ERO Collection should be conserved and preserved.</div>
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<b style="mso-bidi-font-weight: normal;">Hugo Fricke
Collection</b></div>
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Dr. Hugo Fricke was the first
full-time investigator hired by the Long Island Biological Association in 1929.
His research in biophysics, endocrinology, and pharmacology led to future
programs at the cutting edge of scientific research. The collection contains
laboratory notebooks, correspondence, lantern and glass slides, and reprints. </div>
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<b style="mso-bidi-font-weight: normal;">Amos Avery
Photographic Collection</b></div>
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Avery was an associate in plant
breeding for the Carnegie Institution of Washington Department of Genetics.
This collection of photographs, negatives, and scrapbooks gives a view of the
scientific and personal lives of scientists during the early days of the
Department of Genetics.</div>
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<b style="mso-bidi-font-weight: normal;">Barbara McClintock
Collection</b></div>
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Nobel-prize-winning cytogeneticist
Barbara McClintock worked at CSHL for 50 years. The McClintock Collection
contains photographs, correspondence, reprints, and a slide collection, all
annotated by Dr. McClintock. The collection also includes actual corn kernels
and photocopies of Dr. McClintock’s field notebooks and card files. Recently
accessioned materials from Dr. McClintock’s laboratory include books, published
materials, microscope, office equipment, and laboratory equipment.</div>
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<b style="mso-bidi-font-weight: normal;">About this project
and the Documentary Heritage Program, NYS Archives</b></div>
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“Arrangement and Description of the Hidden Collections of
Cold Spring Harbor Laboratory’s Legacy Institutions, 1890-1974” was made
possible in part by a grant from the Documentary Heritage Program of the New
York State Archives, a program of the State Education Department.<span style="mso-spacerun: yes;"> </span>For more information, please visit: <a href="http://www.archives.nysed.gov/a/records/mr_hrecords_dhp.shtml">http://www.archives.nysed.gov/a/records/mr_hrecords_dhp.shtml</a></div>John Zarrillohttp://www.blogger.com/profile/10955424654611881866noreply@blogger.com0tag:blogger.com,1999:blog-858170159917031278.post-2843336079069020622012-07-27T11:16:00.001-04:002012-07-27T11:24:20.300-04:00Eugenics Record Office (ERO) Collection<br />
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<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjqobQNLcjyNzUK8qxcdq-V-dYYEzmOcG3Fib05s1Mq5oFKUBiYAZV33wkHBr-C3SSIkFPTzX2bLtAW9vasG4WeAArsVRw6EDo-vvhkvfniUV7smGGlW3JXhln8ZQNPaZ1qnDOoGc_SNlkb/s1600/Eugenics+Fieldworkers+Conference+1913.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="226" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjqobQNLcjyNzUK8qxcdq-V-dYYEzmOcG3Fib05s1Mq5oFKUBiYAZV33wkHBr-C3SSIkFPTzX2bLtAW9vasG4WeAArsVRw6EDo-vvhkvfniUV7smGGlW3JXhln8ZQNPaZ1qnDOoGc_SNlkb/s320/Eugenics+Fieldworkers+Conference+1913.jpg" width="320" /></a></div>
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The Eugenics Record Office Collection is one of the Archive projects being undertaken as part of the <a href="http://www.archives.nysed.gov/a/grants/grants_dhp.shtml" target="_blank">New York State Documentary Heritage Program Grants</a> (DHP) grant. Specifically, by processing this previously
hidden historic collection materials will be available for scholarly use by
global audiences. </div>
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The Eugenics Record Office (ERO) was
opened in 1910 as part of the Cold Spring Harbor Laboratory then known as the
Carnegie Institute of Washington. Director
Charles Davenport, superintendent H. H. Laughlin, and the office staff studied
problems relating to human heredity until the office closed in 1939. The Eugenics Records Office Collection
includes correspondence, documents and photographs from 1910 to 1939.
Consistent with the social concerns of the period, the ERO studied the heredity
of traits such as "feeble mindedness" and alcoholism, and proposed
that social constructions such as "pauperism" were also
inherited. </div>
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Fieldworkers, primarily women, took
summer training course in heredity, Darwinian theories, elementary statistical
methods, and eugenics legislation. The
fieldworkers worked extensively from 1910 to 1917 taking family histories that
were stored for future studies on diseases and insanity. Approximately 96 fieldworkers collected data
by way of surveys that included biographical sketches and pedigrees on families
from site visits and personal interviews.
Many of the field workers finished the summer with a research project
involving collecting and analyzing the eugenics data. The ERO Collection includes these published
reports. <br />
<br />- E.P., Project Archivist </div>John Zarrillohttp://www.blogger.com/profile/10955424654611881866noreply@blogger.com0tag:blogger.com,1999:blog-858170159917031278.post-83446998506290054362012-07-27T10:19:00.001-04:002012-08-01T08:22:28.701-04:00Watson Named one of the 20 Most Influential Americans of All Time<div class="separator" style="clear: both; text-align: center;">
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<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">This week Time Magazine named Dr. Watson one of the <a href="http://newsfeed.time.com/2012/07/25/the-20-most-influential-americans-of-all-time/#james-watson" style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;" target="_blank">20 Most Influential Americans of All Time</a></span><span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">. The diverse list includes the likes of George Washington, Thomas Edison, Muhammad Ali, and fellow scientist Albert Einstein. </span></div>
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<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">Watson is best known for his role in the discovery of the double helix structure of DNA, but he has also contributed greatly to the sequencing of the human genome (as the first head of the U.S. Human Genome Project) and to cancer research (as Director of Cold Spring Harbor Laboratory). </span></div>
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<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">Click </span><a href="http://newsfeed.time.com/2012/07/25/the-20-most-influential-americans-of-all-time/" style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;" target="_blank">here</a><span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"> to view the entire list.</span></div>
<span id="goog_1870370400"></span><span id="goog_1870370401"></span>John Zarrillohttp://www.blogger.com/profile/10955424654611881866noreply@blogger.com0tag:blogger.com,1999:blog-858170159917031278.post-47142727708894819502012-07-17T11:09:00.002-04:002013-02-27T10:28:27.178-05:00New Exhibit: A Natural Bestseller<div class="separator" style="clear: both; text-align: center;">
<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEibUnEX2Kvsz9ofg5PE635spW-Xhdc0NLCiMyyv2jF38NVbFh7YvLtcLOdmkT6qWtPaw8l02vOPfT9_ww5Z6usvqQz55b9OosZiSTO3xITYoACNf7cI55m_6K38QUfNn8mfm0_X6OOf2tsC/s1600/double+helix+ad+2.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="320" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEibUnEX2Kvsz9ofg5PE635spW-Xhdc0NLCiMyyv2jF38NVbFh7YvLtcLOdmkT6qWtPaw8l02vOPfT9_ww5Z6usvqQz55b9OosZiSTO3xITYoACNf7cI55m_6K38QUfNn8mfm0_X6OOf2tsC/s320/double+helix+ad+2.jpg" width="239" /></a></div>
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<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">CSHL Archives is proud to announce a new exhibit entitled "A Natural Bestseller: The Double Helix" which documents the publication of Dr. Watson's famous memoir using material that has been digitized as part of the "</span><span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"><span style="font-family: "Helvetica Neue", Arial, Helvetica, sans-serif;"><span style="font-size: small;"><span>Codebreakers: Makers of Modern Genetics</span></span></span>" project. The book was controversial when it was released--many praised its unprecedented insight to the personal lives of scientists, while others dismissed it as simply "gossip".</span><span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;"> Francis Crick and Maurice Wilkins, the two other co-recipients of the Nobel Prize for the discovery of the structure of DNA, were both strongly opposed to its release and their threat of legal action led to Watson's American publisher (Harvard University Press) to decided against publishing the book. The exhibit includes a scathing letter from Crick to Watson (6 pages in length) with a laundry list of complaints regarding the manuscript. Crick concludes his letter by noting, "My objection, in short, is to the widespread
dissemination of a book which grossly invades my privacy, and I have
yet to hear an argument which adequately excuses such a violation
of friendship." The letter clearly illustrates why The Double Helix was known as "That Controversial Book".</span><br />
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<span style="font-family: "Helvetica Neue",Arial,Helvetica,sans-serif;">You can view the exhibit online at <a href="http://library.cshl.edu/naturalbestseller/">http://library.cshl.edu/naturalbestseller/</a> or in person at the Cold Spring Harbor Laboratory Library.</span>John Zarrillohttp://www.blogger.com/profile/10955424654611881866noreply@blogger.com0